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Crystal structure of mouse PERK kinase domain

X-ray diffraction
2.81Å resolution
PDB entry 3qd2 coloured by chain, front view.
PDB entry 3qd2 coloured by chain, side view.
PDB entry 3qd2 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Eukaryotic translation initiation factor 2-alpha kinase 3
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-195552

Macromolecules

Eukaryotic translation initiation factor 2-alpha kinase 3
Chain: B
Length: 332 amino acids
Theoretical weight: 38.67 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Z2B5 (Residues: 582-1078; Coverage: 31%)
Gene names: Eif2ak3, Pek, Perk
Pfam: Protein kinase domain
InterPro:
CATH:
Eukaryotic translation initiation factor 2-alpha kinase 3 in PDB entry 3qd2, assembly 1, front view.
Eukaryotic translation initiation factor 2-alpha kinase 3 in PDB entry 3qd2, assembly 1, side view.
Eukaryotic translation initiation factor 2-alpha kinase 3 in PDB entry 3qd2, assembly 1, top view.
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