GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR012754
Domain description:
DNA-directed RNA polymerase, subunit beta-prime, bacterial type
Occurring in:
Occurring in:
IPR010243
Domain description:
DNA-directed RNA polymerase beta subunit, bacterial-type
Occurring in:
Occurring in:
IPR037033
Domain description:
DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
Occurring in:
Occurring in:
IPR007120
Domain description:
DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
Occurring in:
Occurring in:
IPR019462
Domain description:
DNA-directed RNA polymerase, beta subunit, external 1 domain
Occurring in:
Occurring in:
IPR042107
Domain description:
DNA-directed RNA polymerase, beta subunit, external 1 domain superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
3.30.1360.10
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Gyrase A; domain 2
Homology:
RNA polymerase, RBP11-like subunit
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 4 copies of CATH domain <span class='highlight'>3.30.1360.10 (Gyrase A; domain 2)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit alpha</span>. Showing 1 copy in chain <span class='highlight'>G</span>. The deposited structure of PDB entry 4lk1 contains 4 copies of CATH domain 3.30.1360.10 (Gyrase A; domain 2) in DNA-directed RNA polymerase subunit alpha. Showing 1 copy in chain G.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_1_G_CATH_3.30.1360.10_image-200x200.png)
2.40.270.10
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homology:
DNA-directed RNA polymerase, subunit 2, domain 6
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>2.40.270.10 (Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>C</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 2.40.270.10 (Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain C.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_C_CATH_2.40.270.10_image-200x200.png)
1.10.10.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Arc Repressor Mutant, subunit A
Homology:
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 4 copies of CATH domain <span class='highlight'>1.10.10.10 (Arc Repressor Mutant, subunit A)</span> in <span class='highlight'>RNA polymerase sigma factor RpoD</span>. Showing 2 copies in chain <span class='highlight'>F</span>. The deposited structure of PDB entry 4lk1 contains 4 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in RNA polymerase sigma factor RpoD. Showing 2 copies in chain F.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_5_F_CATH_1.10.10.10_image-200x200.png)
1.10.601.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
RNA Polymerase Primary Sigma Factor
Homology:
RNA Polymerase Primary Sigma Factor
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>1.10.601.10 (RNA Polymerase Primary Sigma Factor)</span> in <span class='highlight'>RNA polymerase sigma factor RpoD</span>. Showing 1 copy in chain <span class='highlight'>F</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 1.10.601.10 (RNA Polymerase Primary Sigma Factor) in RNA polymerase sigma factor RpoD. Showing 1 copy in chain F.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_5_F_CATH_1.10.601.10_image-200x200.png)
2.40.50.150
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>2.40.50.150 (OB fold (Dihydrolipoamide Acetyltransferase, E2P))</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>C</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 2.40.50.150 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain C.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_C_CATH_2.40.50.150_image-200x200.png)
2.170.120.12
Class:
Mainly Beta
Architecture:
Beta Complex
Topology:
RNA Polymerase Alpha Subunit; Chain A, domain 2
Homology:
DNA-directed RNA polymerase, insert domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 4 copies of CATH domain <span class='highlight'>2.170.120.12 (RNA Polymerase Alpha Subunit; Chain A, domain 2)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit alpha</span>. Showing 1 copy in chain <span class='highlight'>G</span>. The deposited structure of PDB entry 4lk1 contains 4 copies of CATH domain 2.170.120.12 (RNA Polymerase Alpha Subunit; Chain A, domain 2) in DNA-directed RNA polymerase subunit alpha. Showing 1 copy in chain G.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_1_G_CATH_2.170.120.12_image-200x200.png)
3.90.1100.10
Class:
Alpha Beta
Architecture:
Alpha-Beta Complex
Topology:
Rna Polymerase Beta Subunit; Chain: C,domain 2
Homology:
Rna Polymerase Beta Subunit; Chain: C,domain 2
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 1 copy of CATH domain <span class='highlight'>3.90.1100.10 (Rna Polymerase Beta Subunit; Chain: C,domain 2)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>I</span>. The deposited structure of PDB entry 4lk1 contains 1 copy of CATH domain 3.90.1100.10 (Rna Polymerase Beta Subunit; Chain: C,domain 2) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain I.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_I_CATH_3.90.1100.10_image-200x200.png)
3.90.940.10
Class:
Alpha Beta
Architecture:
Alpha-Beta Complex
Topology:
Eukaryotic RPB6 RNA polymerase subunit
Homology:
Eukaryotic RPB6 RNA polymerase subunit
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>3.90.940.10 (Eukaryotic RPB6 RNA polymerase subunit)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit omega</span>. Showing 1 copy in chain <span class='highlight'>E</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 3.90.940.10 (Eukaryotic RPB6 RNA polymerase subunit) in DNA-directed RNA polymerase subunit omega. Showing 1 copy in chain E.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_4_E_CATH_3.90.940.10_image-200x200.png)
6.10.140.1670
Class:
Special
Architecture:
Helix non-globular
Topology:
Helix Hairpins
Homology:
Helix Hairpins
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>6.10.140.1670 (Helix Hairpins)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>C</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 6.10.140.1670 (Helix Hairpins) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain C.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_C_CATH_6.10.140.1670_image-200x200.png)
2.40.50.100
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>2.40.50.100 (OB fold (Dihydrolipoamide Acetyltransferase, E2P))</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>C</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 2.40.50.100 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain C.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_C_CATH_2.40.50.100_image-200x200.png)
2.30.150.10
Class:
Mainly Beta
Architecture:
Roll
Topology:
Rna Polymerase Beta Subunit; Chain: C, domain 4
Homology:
DNA-directed RNA polymerase, beta subunit, external 1 domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4lk1</span> contains 2 copies of CATH domain <span class='highlight'>2.30.150.10 (Rna Polymerase Beta Subunit; Chain: C, domain 4)</span> in <span class='highlight'>DNA-directed RNA polymerase subunit beta</span>. Showing 1 copy in chain <span class='highlight'>C</span>. The deposited structure of PDB entry 4lk1 contains 2 copies of CATH domain 2.30.150.10 (Rna Polymerase Beta Subunit; Chain: C, domain 4) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain C.](https://www.ebi.ac.uk/pdbe/static/entry/4lk1_2_C_CATH_2.30.150.10_image-200x200.png)