› › Structure analysis

Ancestral Steroid Receptor 2 DNA binding domain in complex with a steroid response element

X-ray diffraction
2.701Å resolution
PDB entry 4oor coloured by chain, front view.
PDB entry 4oor coloured by chain, side view.
PDB entry 4oor coloured by chain, top view.
Source organism: synthetic construct
Assembly composition:
hetero tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero tetramer
Accessible surface area: 12386.65 Å2
Buried surface area: 5404.45 Å2
Dissociation area: 1,249.88 Å2
Dissociation energy (ΔGdiss): 10.96 kcal/mol
Dissociation entropy (TΔSdiss): 11.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-117928
Assembly 2
Download    3D Visualisation
Multimeric state: hetero tetramer
Accessible surface area: 12505.06 Å2
Buried surface area: 5403.89 Å2
Dissociation area: 1,236.08 Å2
Dissociation energy (ΔGdiss): 10.95 kcal/mol
Dissociation entropy (TΔSdiss): 11.02 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-117928

Macromolecules

Ancestral Steroid Receptor 2 DNA binding domain
Chains: A, B, E, F
Length: 82 amino acids
Theoretical weight: 9.04 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
InterPro:
CATH: Erythroid Transcription Factor GATA-1, subunit A
Ancestral Steroid Receptor 2 DNA binding domain in PDB entry 4oor, assembly 1, front view.
Ancestral Steroid Receptor 2 DNA binding domain in PDB entry 4oor, assembly 1, side view.
Ancestral Steroid Receptor 2 DNA binding domain in PDB entry 4oor, assembly 1, top view.
1821020304050607080
 
20406080SPPQKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCLQAGMTLGARKSKKL
Chains
Chain A (auth A)
Chain B (auth B)
RSRZ Outlier Chain C (auth E)
Chain C (auth E)
Chain D (auth F)
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Sequence conservation
Molecule details ›

Search similar proteins

DNA chains I, K
Name: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'
Representative chains: I, K
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.54 KDa
5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, front view.
5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, side view.
5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, top view.
11824681012141618
 
51015CCAGAACAGAGTGTTCTG
Chains
Chain E (auth I)
Chain G (auth K)
Molecule details ›

Search similar DNA

DNA chains J, L
Name: 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'
Representative chains: J, L
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 18 nucleotides
Theoretical weight: 5.47 KDa
5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, front view.
5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, side view.
5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3' in PDB entry 4oor, assembly 1, top view.
11824681012141618
 
51015TCAGAACACTCTGTTCTG
Chains
Chain F (auth J)
Chain H (auth L)
Molecule details ›

Search similar DNA

Quick links