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Allosteric control of the ribosome by small-molecule antibiotics

X-ray diffraction
3.3Å resolution
PDB entry 4v9c coloured by chain, front view.
PDB entry 4v9c coloured by chain, side view.
PDB entry 4v9c coloured by chain, top view.
Source organism: Escherichia coli K-12
Assemblies composition:
hetero 54-mer
hetero 55-mer (preferred)
Entry contents: 50 distinct polypeptide molecules
5 distinct RNA molecules

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Assemblies

Assembly 1
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Assembly Name: ribosomal protein and RNA
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Multimeric state: hetero 54-mer
Accessible surface area: 766559.36 Å2
Buried surface area: 288861.86 Å2
Dissociation area: 849.47 Å2
Dissociation energy (ΔGdiss): 1.08 kcal/mol
Dissociation entropy (TΔSdiss): 13.68 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-135654
Assembly 2 (preferred)
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Multimeric state: hetero 55-mer
Accessible surface area: 772493.45 Å2
Buried surface area: 293794.11 Å2
Dissociation area: 622.86 Å2
Dissociation energy (ΔGdiss): -0.86 kcal/mol
Dissociation entropy (TΔSdiss): 13.62 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-219189

Macromolecules

Small ribosomal subunit protein uS2
Chains: AB, CB
Length: 241 amino acids
Theoretical weight: 26.78 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7V0 (Residues: 1-241; Coverage: 100%)
Gene names: JW0164, b0169, rpsB
Pfam: Ribosomal protein S2
InterPro:
Small ribosomal subunit protein uS2 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS2 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS2 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7V0  
124120406080100120140160180200220240
 
100200
UniProt
P0A7V0
Chains
Domains
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Early folding residue predictions
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Small ribosomal subunit protein uS3
Chains: AC, CC
Length: 233 amino acids
Theoretical weight: 26.03 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7V3 (Residues: 1-233; Coverage: 100%)
Gene names: JW3276, b3314, rpsC
Pfam:
InterPro:
Small ribosomal subunit protein uS3 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS3 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS3 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7V3  
123320406080100120140160180200220
 
100200
UniProt
P0A7V3
Chains
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Small ribosomal subunit protein uS4
Chains: AD, CD
Length: 206 amino acids
Theoretical weight: 23.51 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7V8 (Residues: 1-206; Coverage: 100%)
Gene names: JW3258, b3296, ramA, rpsD
Pfam:
InterPro:
Small ribosomal subunit protein uS4 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS4 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS4 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7V8  
120620406080100120140160180200
 
50100150200
UniProt
P0A7V8
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Small ribosomal subunit protein uS5
Chains: AE, CE
Length: 167 amino acids
Theoretical weight: 17.63 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7W1 (Residues: 1-167; Coverage: 100%)
Gene names: JW3265, b3303, rpsE, spc
Pfam:
InterPro:
Small ribosomal subunit protein uS5 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS5 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS5 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7W1  
116720406080100120140160
 
50100150
UniProt
P0A7W1
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Small ribosomal subunit protein bS6
Chains: AF, CF
Length: 135 amino acids
Theoretical weight: 15.73 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P02358 (Residues: 1-135; Coverage: 100%)
Gene names: JW4158, b4200, rpsF
Pfam: Ribosomal protein S6
InterPro:
Small ribosomal subunit protein bS6 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein bS6 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein bS6 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P02358  
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Small ribosomal subunit protein uS7
Chains: AG, CG
Length: 179 amino acids
Theoretical weight: 20.06 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P02359 (Residues: 1-179; Coverage: 100%)
Gene names: JW3303, b3341, rpsG
Pfam: Ribosomal protein S7p/S5e
InterPro:
Small ribosomal subunit protein uS7 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS7 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS7 in PDB entry 4v9c, assembly 2, top view.
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Small ribosomal subunit protein uS8
Chains: AH, CH
Length: 130 amino acids
Theoretical weight: 14.15 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7W7 (Residues: 1-130; Coverage: 100%)
Gene names: JW3268, b3306, rpsH
Pfam: Ribosomal protein S8
InterPro:
Small ribosomal subunit protein uS8 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS8 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS8 in PDB entry 4v9c, assembly 2, top view.
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Small ribosomal subunit protein uS9
Chains: AI, CI
Length: 130 amino acids
Theoretical weight: 14.89 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7X3 (Residues: 1-130; Coverage: 100%)
Gene names: JW3199, b3230, rpsI
Pfam: Ribosomal protein S9/S16
InterPro:
Small ribosomal subunit protein uS9 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS9 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS9 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7X3  
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Small ribosomal subunit protein uS10
Chains: AJ, CJ
Length: 103 amino acids
Theoretical weight: 11.76 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7R5 (Residues: 1-103; Coverage: 100%)
Gene names: JW3283, b3321, nusE, rpsJ
Pfam: Ribosomal protein S10p/S20e
InterPro:
Small ribosomal subunit protein uS10 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS10 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS10 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7R5  
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Small ribosomal subunit protein uS11
Chains: AK, CK
Length: 129 amino acids
Theoretical weight: 13.87 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7R9 (Residues: 1-129; Coverage: 100%)
Gene names: JW3259, b3297, rpsK
Pfam: Ribosomal protein S11
InterPro:
Small ribosomal subunit protein uS11 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS11 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS11 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7R9  
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Small ribosomal subunit protein uS12
Chains: AL, CL
Length: 124 amino acids
Theoretical weight: 13.77 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7S3 (Residues: 1-124; Coverage: 100%)
Gene names: JW3304, b3342, rpsL, strA
Pfam: Ribosomal protein S12/S23
InterPro:
Small ribosomal subunit protein uS12 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS12 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS12 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7S3  
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Small ribosomal subunit protein uS13
Chains: AM, CM
Length: 118 amino acids
Theoretical weight: 13.13 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7S9 (Residues: 1-118; Coverage: 100%)
Gene names: JW3260, b3298, rpsM
Pfam: Ribosomal protein S13/S18
InterPro:
Small ribosomal subunit protein uS13 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS13 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS13 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7S9  
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Small ribosomal subunit protein uS14
Chains: AN, CN
Length: 101 amino acids
Theoretical weight: 11.61 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG59 (Residues: 1-101; Coverage: 100%)
Gene names: JW3269, b3307, rpsN
Pfam: Ribosomal protein S14p/S29e
InterPro:
Small ribosomal subunit protein uS14 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS14 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS14 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0AG59  
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Small ribosomal subunit protein uS15
Chains: AO, CO
Length: 89 amino acids
Theoretical weight: 10.29 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0ADZ4 (Residues: 1-89; Coverage: 100%)
Gene names: JW3134, b3165, rpsO, secC
Pfam: Ribosomal protein S15
InterPro:
Small ribosomal subunit protein uS15 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS15 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS15 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0ADZ4  
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Small ribosomal subunit protein bS16
Chains: AP, CP
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7T3 (Residues: 1-82; Coverage: 100%)
Gene names: JW2590, b2609, rpsP
Pfam: Ribosomal protein S16
InterPro:
Small ribosomal subunit protein bS16 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein bS16 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein bS16 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7T3  
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Small ribosomal subunit protein uS17
Chains: AQ, CQ
Length: 84 amino acids
Theoretical weight: 9.72 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG63 (Residues: 1-84; Coverage: 100%)
Gene names: JW3273, b3311, neaA, rpsQ
Pfam: Ribosomal protein S17
InterPro:
Small ribosomal subunit protein uS17 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS17 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS17 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0AG63  
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Small ribosomal subunit protein bS18
Chains: AR, CR
Length: 75 amino acids
Theoretical weight: 9.01 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7T7 (Residues: 1-75; Coverage: 100%)
Gene names: JW4160, b4202, rpsR
Pfam: Ribosomal protein S18
InterPro:
Small ribosomal subunit protein bS18 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein bS18 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein bS18 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7T7  
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Small ribosomal subunit protein uS19
Chains: AS, CS
Length: 92 amino acids
Theoretical weight: 10.46 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7U3 (Residues: 1-92; Coverage: 100%)
Gene names: JW3278, b3316, rpsS
Pfam: Ribosomal protein S19
InterPro:
Small ribosomal subunit protein uS19 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein uS19 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein uS19 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7U3  
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Small ribosomal subunit protein bS20
Chains: AT, CT
Length: 87 amino acids
Theoretical weight: 9.71 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7U7 (Residues: 1-87; Coverage: 100%)
Gene names: JW0022, b0023, rpsT
Pfam: Ribosomal protein S20
InterPro:
Small ribosomal subunit protein bS20 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein bS20 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein bS20 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7U7  
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Small ribosomal subunit protein bS21
Chains: AU, CU
Length: 71 amino acids
Theoretical weight: 8.52 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P68679 (Residues: 1-71; Coverage: 100%)
Gene names: JW3037, b3065, rpsU
Pfam: Ribosomal protein S21
InterPro:
Small ribosomal subunit protein bS21 in PDB entry 4v9c, assembly 2, front view.
Small ribosomal subunit protein bS21 in PDB entry 4v9c, assembly 2, side view.
Small ribosomal subunit protein bS21 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P68679  
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Large ribosomal subunit protein uL2
Chains: BC, DC
Length: 273 amino acids
Theoretical weight: 29.92 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P60422 (Residues: 1-273; Coverage: 100%)
Gene names: JW3279, b3317, rplB
Pfam:
InterPro:
Large ribosomal subunit protein uL2 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL2 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL2 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P60422  
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Large ribosomal subunit protein uL3
Chains: BD, DD
Length: 209 amino acids
Theoretical weight: 22.28 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P60438 (Residues: 1-209; Coverage: 100%)
Gene names: JW3282, b3320, rplC
Pfam: Ribosomal protein L3
InterPro:
Large ribosomal subunit protein uL3 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL3 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL3 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P60438  
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Large ribosomal subunit protein uL4
Chains: BE, DE
Length: 201 amino acids
Theoretical weight: 22.12 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P60723 (Residues: 1-201; Coverage: 100%)
Gene names: JW3281, b3319, eryA, rplD
Pfam: Ribosomal protein L4/L1 family
InterPro:
Large ribosomal subunit protein uL4 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL4 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL4 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P60723  
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Large ribosomal subunit protein uL5
Chains: BF, DF
Length: 179 amino acids
Theoretical weight: 20.33 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P62399 (Residues: 1-179; Coverage: 100%)
Gene names: JW3270, b3308, rplE
Pfam:
InterPro:
Large ribosomal subunit protein uL5 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL5 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL5 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P62399  
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Large ribosomal subunit protein uL6
Chains: BG, DG
Length: 177 amino acids
Theoretical weight: 18.93 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG55 (Residues: 1-177; Coverage: 100%)
Gene names: JW3267, b3305, rplF
Pfam: Ribosomal protein L6
InterPro:
Large ribosomal subunit protein uL6 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL6 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL6 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0AG55  
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Large ribosomal subunit protein bL9
Chains: BH, DH
Length: 149 amino acids
Theoretical weight: 15.79 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7R1 (Residues: 1-149; Coverage: 100%)
Gene names: JW4161, b4203, rplI
Pfam:
InterPro:
Large ribosomal subunit protein bL9 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL9 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL9 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7R1  
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Large ribosomal subunit protein uL11
Chains: BI, DI
Length: 142 amino acids
Theoretical weight: 14.89 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7J7 (Residues: 1-142; Coverage: 100%)
Gene names: JW3946, b3983, relC, rplK
Pfam:
InterPro:
Large ribosomal subunit protein uL11 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL11 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL11 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7J7  
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Large ribosomal subunit protein uL13
Chains: BJ, DJ
Length: 142 amino acids
Theoretical weight: 16.05 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AA10 (Residues: 1-142; Coverage: 100%)
Gene names: JW3200, b3231, rplM
Pfam: Ribosomal protein L13
InterPro:
Large ribosomal subunit protein uL13 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL13 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL13 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0AA10  
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Large ribosomal subunit protein uL14
Chains: BK, DK
Length: 123 amino acids
Theoretical weight: 13.57 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0ADY3 (Residues: 1-123; Coverage: 100%)
Gene names: JW3272, b3310, rplN
Pfam: Ribosomal protein L14p/L23e
InterPro:
Large ribosomal subunit protein uL14 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL14 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL14 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0ADY3  
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Large ribosomal subunit protein uL15
Chains: BL, DL
Length: 144 amino acids
Theoretical weight: 15.01 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P02413 (Residues: 1-144; Coverage: 100%)
Gene names: JW3263, b3301, rplO
Pfam: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
InterPro:
Large ribosomal subunit protein uL15 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL15 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL15 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P02413  
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Large ribosomal subunit protein uL16
Chains: BM, DM
Length: 136 amino acids
Theoretical weight: 15.31 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0ADY7 (Residues: 1-136; Coverage: 100%)
Gene names: JW3275, b3313, rplP
Pfam: Ribosomal protein L16p/L10e
InterPro:
Large ribosomal subunit protein uL16 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL16 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL16 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0ADY7  
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Large ribosomal subunit protein bL17
Chains: BN, DN
Length: 127 amino acids
Theoretical weight: 14.39 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG44 (Residues: 1-127; Coverage: 100%)
Gene names: JW3256, b3294, rplQ
Pfam: Ribosomal protein L17
InterPro:
Large ribosomal subunit protein bL17 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL17 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL17 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0AG44  
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Large ribosomal subunit protein uL18
Chains: BO, DO
Length: 117 amino acids
Theoretical weight: 12.79 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0C018 (Residues: 1-117; Coverage: 100%)
Gene names: JW3266, b3304, rplR
Pfam: Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
InterPro:
Large ribosomal subunit protein uL18 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL18 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL18 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0C018  
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Large ribosomal subunit protein bL19
Chains: BP, DP
Length: 115 amino acids
Theoretical weight: 13.16 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7K6 (Residues: 1-115; Coverage: 100%)
Gene names: JW2587, b2606, rplS
Pfam: Ribosomal protein L19
InterPro:
Large ribosomal subunit protein bL19 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL19 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL19 in PDB entry 4v9c, assembly 2, top view.
PDBe-KB: UniProt Coverage View: P0A7K6  
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Large ribosomal subunit protein bL20
Chains: BQ, DQ
Length: 118 amino acids
Theoretical weight: 13.53 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7L3 (Residues: 1-118; Coverage: 100%)
Gene names: JW1706, b1716, pdzA, rplT
Pfam: Ribosomal protein L20
InterPro:
Large ribosomal subunit protein bL20 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL20 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL20 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL21
Chains: BR, DR
Length: 103 amino acids
Theoretical weight: 11.59 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG48 (Residues: 1-103; Coverage: 100%)
Gene names: JW3153, b3186, rplU
Pfam: Ribosomal prokaryotic L21 protein
InterPro:
Large ribosomal subunit protein bL21 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL21 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL21 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein uL22
Chains: BS, DS
Length: 110 amino acids
Theoretical weight: 12.25 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P61175 (Residues: 1-110; Coverage: 100%)
Gene names: JW3277, b3315, eryB, rplV
Pfam: Ribosomal protein L22p/L17e
InterPro:
Large ribosomal subunit protein uL22 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL22 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL22 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein uL23
Chains: BT, DT
Length: 100 amino acids
Theoretical weight: 11.22 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0ADZ0 (Residues: 1-100; Coverage: 100%)
Gene names: JW3280, b3318, rplW
Pfam: Ribosomal protein L23
InterPro:
Large ribosomal subunit protein uL23 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL23 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL23 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein uL24
Chains: BU, DU
Length: 104 amino acids
Theoretical weight: 11.34 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P60624 (Residues: 1-104; Coverage: 100%)
Gene names: JW3271, b3309, rplX
Pfam:
InterPro:
Large ribosomal subunit protein uL24 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL24 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL24 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL25
Chains: BV, DV
Length: 94 amino acids
Theoretical weight: 10.71 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P68919 (Residues: 1-94; Coverage: 100%)
Gene names: JW2173, b2185, rplY
Pfam: Ribosomal L25p family
InterPro:
Large ribosomal subunit protein bL25 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL25 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL25 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL27
Chains: BW, DW
Length: 85 amino acids
Theoretical weight: 9.15 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7L8 (Residues: 1-85; Coverage: 100%)
Gene names: JW3152, b3185, rpmA
Pfam: Ribosomal L27 protein
InterPro:
Large ribosomal subunit protein bL27 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL27 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL27 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL28
Chains: BX, DX
Length: 78 amino acids
Theoretical weight: 9.03 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7M2 (Residues: 1-78; Coverage: 100%)
Gene names: JW3612, b3637, rpmB
Pfam: Ribosomal L28 family
InterPro:
Large ribosomal subunit protein bL28 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL28 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL28 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein uL29
Chains: BY, DY
Length: 63 amino acids
Theoretical weight: 7.29 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7M6 (Residues: 1-63; Coverage: 100%)
Gene names: JW3274, b3312, rpmC
Pfam: Ribosomal L29 protein
InterPro:
Large ribosomal subunit protein uL29 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL29 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL29 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein uL30
Chains: BZ, DZ
Length: 59 amino acids
Theoretical weight: 6.55 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0AG51 (Residues: 1-59; Coverage: 100%)
Gene names: JW3264, b3302, rpmD
Pfam: Ribosomal protein L30p/L7e
InterPro:
Large ribosomal subunit protein uL30 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein uL30 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein uL30 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL32
Chains: B0, D0
Length: 57 amino acids
Theoretical weight: 6.46 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7N4 (Residues: 1-57; Coverage: 100%)
Gene names: JW1075, b1089, rpmF
Pfam: Ribosomal L32p protein family
InterPro:
Large ribosomal subunit protein bL32 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL32 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL32 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL33
Chains: B1, D1
Length: 55 amino acids
Theoretical weight: 6.39 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7N9 (Residues: 1-55; Coverage: 100%)
Gene names: JW3611, b3636, rpmG
Pfam: Ribosomal protein L33
InterPro:
Large ribosomal subunit protein bL33 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL33 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL33 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL34
Chains: B2, D2
Length: 46 amino acids
Theoretical weight: 5.4 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7P5 (Residues: 1-46; Coverage: 100%)
Gene names: JW3680, b3703, rimA, rpmH, ssaF
Pfam: Ribosomal protein L34
InterPro:
Large ribosomal subunit protein bL34 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL34 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL34 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL35
Chains: B3, D3
Length: 65 amino acids
Theoretical weight: 7.31 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7Q1 (Residues: 1-65; Coverage: 100%)
Gene names: JW1707, b1717, rpmI
Pfam: Ribosomal protein L35
InterPro:
Large ribosomal subunit protein bL35 in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL35 in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL35 in PDB entry 4v9c, assembly 2, top view.
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Large ribosomal subunit protein bL36A
Chains: B4, D4
Length: 38 amino acids
Theoretical weight: 4.38 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A7Q6 (Residues: 1-38; Coverage: 100%)
Gene names: JW3261, b3299, rpmJ
Pfam: Ribosomal protein L36
InterPro:
Large ribosomal subunit protein bL36A in PDB entry 4v9c, assembly 2, front view.
Large ribosomal subunit protein bL36A in PDB entry 4v9c, assembly 2, side view.
Large ribosomal subunit protein bL36A in PDB entry 4v9c, assembly 2, top view.
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Ribosome-recycling factor
Chain: CY
Length: 185 amino acids
Theoretical weight: 20.67 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0A805 (Residues: 1-185; Coverage: 100%)
Gene names: JW0167, b0172, frr, rrf
Pfam: Ribosome recycling factor
InterPro:
Ribosome-recycling factor in PDB entry 4v9c, assembly 2, front view.
Ribosome-recycling factor in PDB entry 4v9c, assembly 2, side view.
Ribosome-recycling factor in PDB entry 4v9c, assembly 2, top view.
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RNA chains AA, CA
Name: 16S ribosomal RNA
Representative chains: AA, CA
Length: 1542 nucleotides
Theoretical weight: 499.69 KDa
Rfam: Bacterial small subunit ribosomal RNA
16S ribosomal RNA in PDB entry 4v9c, assembly 2, front view.
16S ribosomal RNA in PDB entry 4v9c, assembly 2, side view.
16S ribosomal RNA in PDB entry 4v9c, assembly 2, top view.
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RNA chains AV, CV
Name: Phenylalanine specific transfer RNA, tRNA-Phe
Representative chains: AV, CV
Length: 76 nucleotides
Theoretical weight: 24.49 KDa
Rfam: tRNA
Phenylalanine specific transfer RNA, tRNA-Phe in PDB entry 4v9c, assembly 2, front view.
Phenylalanine specific transfer RNA, tRNA-Phe in PDB entry 4v9c, assembly 2, side view.
Phenylalanine specific transfer RNA, tRNA-Phe in PDB entry 4v9c, assembly 2, top view.
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RNA chains AX, CX
Name: Messenger RNA
Representative chains: AX, CX
Length: 24 nucleotides
Theoretical weight: 7.79 KDa
Messenger RNA in PDB entry 4v9c, assembly 2, front view.
Messenger RNA in PDB entry 4v9c, assembly 2, side view.
Messenger RNA in PDB entry 4v9c, assembly 2, top view.
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RNA chains BA, DA
Name: 23S ribosomal RNA
Representative chains: BA, DA
Length: 2904 nucleotides
Theoretical weight: 941.61 KDa
Rfam: Bacterial large subunit ribosomal RNA
23S ribosomal RNA in PDB entry 4v9c, assembly 2, front view.
23S ribosomal RNA in PDB entry 4v9c, assembly 2, side view.
23S ribosomal RNA in PDB entry 4v9c, assembly 2, top view.
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RNA chains BB, DB
Name: 5S ribosomal RNA
Representative chains: BB, DB
Length: 120 nucleotides
Theoretical weight: 38.79 KDa
Rfam: 5S ribosomal RNA
5S ribosomal RNA in PDB entry 4v9c, assembly 2, front view.
5S ribosomal RNA in PDB entry 4v9c, assembly 2, side view.
5S ribosomal RNA in PDB entry 4v9c, assembly 2, top view.
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