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4xah › Structure analysis

X-ray crystal structure of S. cerevisiae Cgi121

X-ray diffraction

2.5Å resolution

PDB entry 4xah coloured by chain, front view.

PDB entry 4xah coloured by chain, side view.

PDB entry 4xah coloured by chain, top view.

Source organism: Saccharomyces cerevisiae S288C

Assembly composition:

monomeric (preferred)

Entry contents: 1 distinct polypeptide molecule

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4xah overview
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Assembly composition XML
Assembly 1 (mmCIF; gz)
Assembly 2 (mmCIF; gz)
Assembly 1 (atom only; mmCIF)
Assembly 2 (atom only; mmCIF)
Archive mmCIF file
Updated mmCIF file
PDB file
PDB header
PDB file (gz)
PDBML
PDBML (ATOM lines)
PDBML (no atoms)
Structure Factors
EDS map
EDS difference map
FASTA (Entry)

Assemblies

Assembly 1 (preferred)

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Assembly Name: EKC/KEOPS complex subunit CGI121
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Multimeric state: monomeric

Accessible surface area: 9086.8 Å²

Buried surface area: 0.0 Å²

Dissociation area: 0 Å²

Dissociation energy (ΔG^diss): 0 kcal/mol

Dissociation entropy (TΔS^diss): 0 kcal/mol

Symmetry number: 1

PDBe Complex ID: PDB-CPX-169932

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, front view.

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, side view.

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, top view.

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, front view.

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, side view.

Monomeric assembly 1 of PDB entry 4xah coloured by chemically distinct molecules, top view.

Assembly 2

Download 3D Visualisation

Assembly Name: EKC/KEOPS complex subunit CGI121
hide full assembly name

Multimeric state: monomeric

Accessible surface area: 9211.45 Å²

Buried surface area: 0.0 Å²

Dissociation area: 0 Å²

Dissociation energy (ΔG^diss): 0 kcal/mol

Dissociation entropy (TΔS^diss): 0 kcal/mol

Symmetry number: 1

PDBe Complex ID: PDB-CPX-169932

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, front view.

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, side view.

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, top view.

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, front view.

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, side view.

Monomeric assembly 2 of PDB entry 4xah coloured by chemically distinct molecules, top view.

Macromolecules

EKC/KEOPS complex subunit CGI121

Chains: A, B
Length: 187 amino acids
Theoretical weight: 21.59 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:

Canonical: Q03705 (Residues: 1-181; Coverage: 100%)

Gene names: CGI121, YML036W
Pfam: Kinase binding protein CGI-121
InterPro:

CGI121/TPRKB superfamily
CGI121/TPRKB

CATH: CGI121/TPRKB

EKC/KEOPS complex subunit CGI121 in PDB entry 4xah, assembly 1, front view.

EKC/KEOPS complex subunit CGI121 in PDB entry 4xah, assembly 1, side view.

EKC/KEOPS complex subunit CGI121 in PDB entry 4xah, assembly 1, top view.

FASTA Sequence


    >pdb|4xah|A B

MVVSIIPQFPDIKVSLALFEQVKNAKEIRSKMSELSTSFAFIDPRLVCSGEQMYSAIYKTLIEVKYNKMRTRNLNSECVLCLSPTSNISDAFLKFGIKDDSSQLICLKFHTNTDDVDKEQLRTIMTSIVKGQEIEFNDDNLSRFYDEALIRKIYKLSDDFKPQDVNGLSRALVDAIQLRGVHHHHHH

PDBe-KB: UniProt Coverage View: Q03705

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UniProt

Q03705

Mapping to UniProt CG121_YEAST

Chains

RSRZ Outlier Chain A

Chain A

RSRZ Outlier Chain B

Chain B

Domains

Residues mapped to CATH domains

Residues mapped to InterPro annotations

Secondary structure

Residues forming Helix

Residues forming Strand

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Flexibility predictions

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Early folding residue predictions

Sequence conservation

Amino acid probabilities The amino acid probabilities are calculated using HMM profiles based on multiple sequence alignments. Click to see more details...

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Amino acid properties

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Molecule details ›

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FASTA (Protein chains A, B)
Archive mmCIF file
Updated mmCIF file
PDB file
PDB header
PDB file (gz)
PDBML
PDBML (ATOM lines)
PDBML (no atoms)
Structure Factors
SIFTS XML file with residue-level mappings

Search similar proteins

Similar 3D structures (PDBeFold)
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BLAST Q03705 (UniProt)

Quick links

4xah overview
- Citations
Structure analysis
Function and Biology
Ligands and Environments
Experiments and Validation

Downloads

Close

Assembly composition XML
Assembly 1 (mmCIF; gz)
Assembly 2 (mmCIF; gz)
Assembly 1 (atom only; mmCIF)
Assembly 2 (atom only; mmCIF)
Archive mmCIF file
Updated mmCIF file
PDB file
PDB header
PDB file (gz)
PDBML
PDBML (ATOM lines)
PDBML (no atoms)
Structure Factors
EDS map
EDS difference map
FASTA (Entry)

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