EC 3.4.22.61: Caspase-8
Reaction catalysed:
Strict requirement for Asp at position P1 and has a preferred cleavage sequence of (Leu/Asp/Val)-Glu-Thr-Asp-|-(Gly/Ser/Ala)
Systematic name:
-
Alternative Name(s):
- Apoptotic cysteine protease
- Apoptotic protease Mch-5
- CAP4
- CASP-8
- FADD-homologous ICE/CED-3-like protease
- FADD-like ICE
- FLICE
- ICE-like apoptotic protease 5
- MACH
- MORT1-associated CED-3 homolog
- Mammalian Ced-3 homolog 5
- Mch5
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Protein family (Pfam)
InterPro annotations
CATH domain