Function and Biology

Phosphorylated MAVS in complex with IRF-3

Source organism: Homo sapiens
Biochemical function: DNA-binding transcription factor activity
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF10401
Domain description: Interferon-regulatory factor 3
Occurring in:
  1. Interferon regulatory factor 3
The deposited structure of PDB entry 5jek contains 2 copies of Pfam domain PF10401 (Interferon-regulatory factor 3) in Interferon regulatory factor 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR019471
Domain description: Interferon regulatory factor-3
Occurring in:
  1. Interferon regulatory factor 3
IPR008984
Domain description: SMAD/FHA domain superfamily
Occurring in:
  1. Interferon regulatory factor 3
IPR017855
Domain description: SMAD-like domain superfamily
Occurring in:
  1. Interferon regulatory factor 3

Structure domain

CATH CATH domain
2.60.200.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Tumour Suppressor Smad4
Homology: Tumour Suppressor Smad4
Occurring in:
  1. Interferon regulatory factor 3
The deposited structure of PDB entry 5jek contains 2 copies of CATH domain 2.60.200.10 (Tumour Suppressor Smad4) in Interferon regulatory factor 3. Showing 1 copy in chain A.