Function and Biology Details
Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Glycoprotein E, immunoglobulin-like domain, flavivirus
- Envelope glycoprotein M superfamily, flavivirus
- Envelope glycoprotein M, flavivirus
- Flavivirus envelope glycoprotein E, Stem/Anchor domain superfamily
- Flavivirus envelope glycoprotein E, Stem/Anchor domain
- Flavivirus polyprotein propeptide
- Flavivirus polyprotein propeptide superfamily
- Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily
6 more domains
Structure analysis Details
Assembly composition:
hetero 720-mer (preferred)
PDBe Complex ID:
PDB-CPX-100070 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
E protein
Molecule details ›
Chains: A, C, E
Length: 402 amino acids
Theoretical weight: 44.8 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
Length: 402 amino acids
Theoretical weight: 44.8 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
O11875 (Residues: 281-674; Coverage: 12%)
pr domain
Molecule details ›
Chains: B, D, F
Length: 81 amino acids
Theoretical weight: 9.26 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
Length: 81 amino acids
Theoretical weight: 9.26 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
- Canonical: A0A0B4L3F2 (Residues: 115-195; Coverage: 2%)
Envelope protein E
Molecule details ›
Chains: G, I, K
Length: 66 amino acids
Theoretical weight: 6.89 KDa
Source organism: Zika virus
UniProt:
Length: 66 amino acids
Theoretical weight: 6.89 KDa
Source organism: Zika virus
UniProt:
- Canonical: A0A024B7W1 (Residues: 726-791; Coverage: 2%)
Small envelope protein M
Molecule details ›
Chains: H, J, L
Length: 53 amino acids
Theoretical weight: 5.98 KDa
Source organism: Zika virus
UniProt:
Length: 53 amino acids
Theoretical weight: 5.98 KDa
Source organism: Zika virus
UniProt:
- Canonical: A0A024B7W1 (Residues: 238-290; Coverage: 2%)
