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DHp domain of PhoR of M. tuberculosis - native data

X-ray diffraction
2.02Å resolution
PDB entry 5uky coloured by chain, front view.
PDB entry 5uky coloured by chain, side view.
PDB entry 5uky coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: histidine kinase
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Multimeric state: homo dimer
Accessible surface area: 9031.69 Å2
Buried surface area: 5504.33 Å2
Dissociation area: 1,994.7 Å2
Dissociation energy (ΔGdiss): 20.13 kcal/mol
Dissociation entropy (TΔSdiss): 11.16 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-159818

Macromolecules

histidine kinase
Chains: A, B
Length: 74 amino acids
Theoretical weight: 8.36 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P71815 (Residues: 240-310; Coverage: 15%)
Gene names: Rv0758, phoR
Pfam: His Kinase A (phospho-acceptor) domain
InterPro:
histidine kinase in PDB entry 5uky, assembly 1, front view.
histidine kinase in PDB entry 5uky, assembly 1, side view.
histidine kinase in PDB entry 5uky, assembly 1, top view.
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