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Crystal structure of a glycine hydroxymethyltransferase from Acinetobacter baumannii

X-ray diffraction
2.5Å resolution
PDB entry 5vmb coloured by chain, front view.
PDB entry 5vmb coloured by chain, side view.
PDB entry 5vmb coloured by chain, top view.
Source organism: Acinetobacter baumannii
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine hydroxymethyltransferase
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Multimeric state: monomeric
Accessible surface area: 17468.16 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-197640
Assembly 2
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Assembly Name: Serine hydroxymethyltransferase
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Multimeric state: homo dimer
Accessible surface area: 27525.26 Å2
Buried surface area: 7420.87 Å2
Dissociation area: 3,710.43 Å2
Dissociation energy (ΔGdiss): 51.07 kcal/mol
Dissociation entropy (TΔSdiss): 14.86 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-197641

Macromolecules

Serine hydroxymethyltransferase
Chain: A
Length: 425 amino acids
Theoretical weight: 46.08 KDa
Source organism: Acinetobacter baumannii
Expression system: Escherichia coli
UniProt:
  • Canonical: V5VBJ2 (Residues: 1-417; Coverage: 100%)
Gene names: A7M90_04720, ABR2091_2493, ABUW_1333, APD33_02225, AUO97_00455, B9W25_05820, B9X95_16385, CBE85_00370, CPI82_15840, CV954_006065, DOL94_04740, EA706_00855, EA722_04005, EJ062_01385, EKS29_06695, F2P40_02110, F4T85_00485, FJU42_09815, FJU79_05920, FPK81_01880, FQZ18_06445, G3N53_09830, GNY86_18470, GSE42_13680, H0529_01320, IAG11_02380, J6E47_06215, JHZ39_000903, LV35_02351, MKP18_000318, P9867_012380, P9867_01620, SAMEA104305340_01960, SAMEA4394745_01948, glyA, glyA2
Pfam: Serine hydroxymethyltransferase
InterPro:
CATH:
Serine hydroxymethyltransferase in PDB entry 5vmb, assembly 1, front view.
Serine hydroxymethyltransferase in PDB entry 5vmb, assembly 1, side view.
Serine hydroxymethyltransferase in PDB entry 5vmb, assembly 1, top view.
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