Structure analysis

The crystal structure of the apo form of Mtb MazF

X-ray diffraction
2.356Å resolution
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 10098.85 Å2
Buried surface area: 2013.16 Å2
Dissociation area: 1,006.58 Å2
Dissociation energy (ΔGdiss): 9.92 kcal/mol
Dissociation entropy (TΔSdiss): 11.14 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-143535

Macromolecules

Chains: A, C
Length: 140 amino acids
Theoretical weight: 14.65 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CL62 (Residues: 1-136; Coverage: 100%)
Gene names: Rv2063A, mazF7
Pfam: PemK-like, MazF-like toxin of type II toxin-antitoxin system
InterPro:

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