› › Structure analysis

CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex

Electron Microscopy
4.5Å resolution
PDB entry 6c14 coloured by chain, front view.
PDB entry 6c14 coloured by chain, side view.
PDB entry 6c14 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: LHFPL tetraspan subfamily member 5 protein and Protocadherin-15
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 44526.36 Å2
Buried surface area: 10602.35 Å2
Dissociation area: 2,611.24 Å2
Dissociation energy (ΔGdiss): 27.86 kcal/mol
Dissociation entropy (TΔSdiss): 15.48 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-175631

Macromolecules

Protocadherin-15
Chains: A, C
Length: 337 amino acids
Theoretical weight: 37.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99PJ1 (Residues: 1144-1465; Coverage: 17%)
  • Best match: Q99PJ1-10 (Residues: 1151-1472)
Gene name: Pcdh15
Pfam: Cadherin domain
InterPro:
Protocadherin-15 in PDB entry 6c14, assembly 1, front view.
Protocadherin-15 in PDB entry 6c14, assembly 1, side view.
Protocadherin-15 in PDB entry 6c14, assembly 1, top view.
Molecule details ›

Search similar proteins

LHFPL tetraspan subfamily member 5 protein
Chains: B, D
Length: 228 amino acids
Theoretical weight: 25.07 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q4KL25 (Residues: 1-219; Coverage: 100%)
Gene names: Lhfpl5, Tmhs
Pfam: Lipoma HMGIC fusion partner-like protein
InterPro: Lipoma HMGIC fusion partner-like protein
LHFPL tetraspan subfamily member 5 protein in PDB entry 6c14, assembly 1, front view.
LHFPL tetraspan subfamily member 5 protein in PDB entry 6c14, assembly 1, side view.
LHFPL tetraspan subfamily member 5 protein in PDB entry 6c14, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links