Assemblies
Assembly Name:
Protein argonaute-2 and RNA
Multimeric state:
hetero trimer
Accessible surface area:
36311.8 Å2
Buried surface area:
8445.39 Å2
Dissociation area:
1,613.04
Å2
Dissociation energy (ΔGdiss):
4.72
kcal/mol
Dissociation entropy (TΔSdiss):
10.05
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-193885
Macromolecules
Chain: A
Length: 859 amino acids
Theoretical weight: 97.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam:
Length: 859 amino acids
Theoretical weight: 97.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9UKV8 (Residues: 1-859; Coverage: 100%)
Pfam:
- N-terminal domain of argonaute
- Argonaute linker 1 domain
- PAZ domain
- Argonaute linker 2 domain
- Mid domain of argonaute
- Piwi domain
- Protein argonaute-2
- Protein argonaute, N-terminal
- PAZ domain superfamily
- Argonaute, linker 1 domain
- PAZ domain
- Argonaute linker 2 domain
- Argonaute-like, PIWI domain
- Protein argonaute, Mid domain
- Ribonuclease H-like superfamily
- Piwi domain
- Ribonuclease H superfamily
Name:
Guide RNA
Representative chains: B
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 21 nucleotides
Theoretical weight: 6.55 KDa
Representative chains: B
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 21 nucleotides
Theoretical weight: 6.55 KDa
Name:
Target RNA
Representative chains: C
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 11 nucleotides
Theoretical weight: 3.54 KDa
Representative chains: C
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 11 nucleotides
Theoretical weight: 3.54 KDa