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Apo structure of the mitochondrial calcium uniporter protein MICU2

X-ray diffraction
2.504Å resolution
PDB entry 6eaz coloured by chain, front view.
PDB entry 6eaz coloured by chain, side view.
PDB entry 6eaz coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Calcium uptake protein 2, mitochondrial
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Multimeric state: homo dimer
Accessible surface area: 34503.33 Å2
Buried surface area: 4843.49 Å2
Dissociation area: 1,421.98 Å2
Dissociation energy (ΔGdiss): 13.76 kcal/mol
Dissociation entropy (TΔSdiss): 14.31 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-183949

Macromolecules

Calcium uptake protein 2, mitochondrial
Chains: A, B
Length: 379 amino acids
Theoretical weight: 44.55 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8CD10 (Residues: 68-432; Coverage: 85%)
Gene names: Efha1, Micu2
InterPro:
Calcium uptake protein 2, mitochondrial in PDB entry 6eaz, assembly 1, front view.
Calcium uptake protein 2, mitochondrial in PDB entry 6eaz, assembly 1, side view.
Calcium uptake protein 2, mitochondrial in PDB entry 6eaz, assembly 1, top view.
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