Assemblies
Assembly Name:
DNA-directed RNA and RNA and DNA
Multimeric state:
hetero pentadecamer
Accessible surface area:
158741.43 Å2
Buried surface area:
74166.74 Å2
Dissociation area:
2,101.29
Å2
Dissociation energy (ΔGdiss):
9.22
kcal/mol
Dissociation entropy (TΔSdiss):
11.32
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-119994
Macromolecules
Chain: A
Length: 1664 amino acids
Theoretical weight: 186.68 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam:
Length: 1664 amino acids
Theoretical weight: 186.68 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P10964 (Residues: 1-1664; Coverage: 100%)
Pfam:
- RNA polymerase Rpb1, domain 1
- RNA polymerase Rpb1, domain 2
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
- RNA polymerase Rpb1, clamp domain superfamily
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA pol I, largest subunit, N-terminal domain
- DNA-directed RNA polymerase, subunit beta-prime
- RNA polymerase, N-terminal
- RNA polymerase, alpha subunit
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 3 superfamily
- RNA polymerase Rpb1, funnel domain superfamily
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
- DNA-directed RNA pol I, largest subunit, C-terminal domain
Chain: B
Length: 1203 amino acids
Theoretical weight: 135.91 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam:
Length: 1203 amino acids
Theoretical weight: 135.91 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P22138 (Residues: 1-1203; Coverage: 100%)
Pfam:
- RNA polymerase beta subunit
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 3
- RNA polymerase I, Rpa2 specific domain
- RNA polymerase Rpb2, domain 6
- RNA polymerase Rpb2, domain 7
- DNA-directed RNA polymerase, subunit 2
- RNA polymerase, beta subunit, protrusion
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 2 superfamily
- RNA polymerase Rpb2, domain 3
- DNA-directed RNA polymerase I subunit RPA2, domain 4
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
- RNA polymerase Rpb2, OB-fold
- RNA polymerase, beta subunit, conserved site
- RNA polymerase Rpb2, domain 7
Chain: C
Length: 335 amino acids
Theoretical weight: 37.73 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam:
InterPro:
Length: 335 amino acids
Theoretical weight: 37.73 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P07703 (Residues: 1-335; Coverage: 100%)
Pfam:
InterPro:
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerases I and III subunit AC40
- DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, insert domain
Chain: D
Length: 137 amino acids
Theoretical weight: 14.6 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: Yeast RNA polymerase I subunit RPA14
InterPro: RNA polymerase I, subunit Rpa14, fungi
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 137 amino acids
Theoretical weight: 14.6 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P50106 (Residues: 1-137; Coverage: 100%)
Pfam: Yeast RNA polymerase I subunit RPA14
InterPro: RNA polymerase I, subunit Rpa14, fungi
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Chain: E
Length: 215 amino acids
Theoretical weight: 25.12 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam:
InterPro:
Length: 215 amino acids
Theoretical weight: 25.12 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P20434 (Residues: 1-215; Coverage: 100%)
Pfam:
InterPro:
- DNA-directed RNA polymerase subunit Rpo5/Rpb5
- RNA polymerase Rpb5, N-terminal domain superfamily
- RNA polymerase, Rpb5, N-terminal
- RPB5-like RNA polymerase subunit superfamily
- RNA polymerase, subunit H/Rpb5 C-terminal
- RNA polymerase, subunit H/Rpb5, conserved site
Chain: F
Length: 155 amino acids
Theoretical weight: 17.93 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: RNA polymerase Rpb6
InterPro:
Length: 155 amino acids
Theoretical weight: 17.93 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P20435 (Residues: 1-155; Coverage: 100%)
Pfam: RNA polymerase Rpb6
InterPro:
- Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
- DNA-directed RNA polymerase, subunit RPB6
- RPB6/omega subunit-like superfamily
- RNA polymerase, subunit omega/Rpo6/RPB6
- DNA-directed RNA polymerase, 14-18kDa subunit, conserved site
Chain: H
Length: 146 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: RNA polymerase Rpb8
InterPro:
CATH: Nucleic acid-binding proteins
Length: 146 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P20436 (Residues: 1-146; Coverage: 100%)
Pfam: RNA polymerase Rpb8
InterPro:
CATH: Nucleic acid-binding proteins
Chain: J
Length: 70 amino acids
Theoretical weight: 8.29 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:
Length: 70 amino acids
Theoretical weight: 8.29 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P22139 (Residues: 1-70; Coverage: 100%)
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:
- DNA-directed RNA polymerase subunit RPABC5/Rpb10
- RNA polymerase subunit RPB10
- RNA polymerases, subunit N, zinc binding site
Chain: K
Length: 142 amino acids
Theoretical weight: 16.17 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain
InterPro:
Length: 142 amino acids
Theoretical weight: 16.17 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P28000 (Residues: 1-142; Coverage: 100%)
Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain
InterPro:
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerases I and III subunit AC19
- DNA-directed RNA polymerase subunit Rpo11-like
- DNA-directed RNA polymerase, RBP11-like dimerisation domain
- DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
Chain: L
Length: 70 amino acids
Theoretical weight: 7.73 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
Pfam: DNA directed RNA polymerase, 7 kDa subunit
InterPro:
Length: 70 amino acids
Theoretical weight: 7.73 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
- Canonical: P40422 (Residues: 1-70; Coverage: 100%)
Pfam: DNA directed RNA polymerase, 7 kDa subunit
InterPro:
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
- RNA polymerase subunit RPABC4/transcription elongation factor Spt4
Name:
Non-template strand
Representative chains: S
Length: 38 nucleotides
Theoretical weight: 11.76 KDa
Representative chains: S
Length: 38 nucleotides
Theoretical weight: 11.76 KDa