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Crystal structure of (E)-biformene synthase LrdC from Streptomyces sp. strain K155 in complex with Mg and PPi

X-ray diffraction
2.07Å resolution
PDB entry 6oh6 coloured by chain, front view.
PDB entry 6oh6 coloured by chain, side view.
PDB entry 6oh6 coloured by chain, top view.
Source organism: Streptomyces sp.
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Terpene synthase
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Multimeric state: homo dimer
Accessible surface area: 25003.91 Å2
Buried surface area: 6708.3 Å2
Dissociation area: 1,771.97 Å2
Dissociation energy (ΔGdiss): 5.78 kcal/mol
Dissociation entropy (TΔSdiss): 13.73 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-495210

Macromolecules

Terpene synthase
Chain: A
Length: 342 amino acids
Theoretical weight: 37.24 KDa
Source organism: Streptomyces sp.
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A158RFK9 (Residues: 1-342; Coverage: 100%)
Pfam: Terpene synthase family 2, C-terminal metal binding
InterPro:
CATH: Farnesyl Diphosphate Synthase
Terpene synthase in PDB entry 6oh6, assembly 1, front view.
Terpene synthase in PDB entry 6oh6, assembly 1, side view.
Terpene synthase in PDB entry 6oh6, assembly 1, top view.
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