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Amyloid-Beta (20-34) wild type

Electron crystallography
1.1Å resolution
PDB entry 6oiz coloured by chain, front view.
PDB entry 6oiz coloured by chain, side view.
PDB entry 6oiz coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo pentamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Soluble APP-beta
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Multimeric state: homo pentamer
Accessible surface area: 3669.59 Å2
Buried surface area: 4312.26 Å2
Dissociation area: 2,156.13 Å2
Dissociation energy (ΔGdiss): 14.39 kcal/mol
Dissociation entropy (TΔSdiss): 29.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138401

Macromolecules

P3(40)
Chain: A
Length: 15 amino acids
Theoretical weight: 1.49 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 691-705; Coverage: 2%)
Gene names: A4, AD1, APP
Pfam: Beta-amyloid peptide (beta-APP)
InterPro:
P3(40) in PDB entry 6oiz, assembly 1, front view.
P3(40) in PDB entry 6oiz, assembly 1, side view.
P3(40) in PDB entry 6oiz, assembly 1, top view.
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