Structure analysis

Ovine respiratory complex I FRC open class 6

Electron Microscopy
6.5Å resolution
Source organism: Ovis aries
Assembly composition:
hetero 45-mer (preferred)
Entry contents: 44 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero 45-mer
PDBe Complex ID: PDB-CPX-131288

Macromolecules

Search similar proteins

Chain: V2
Length: 217 amino acids
Theoretical weight: 23.84 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5NRY1 (Residues: 30-246; Coverage: 88%)
Gene name: NDUFV2
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Chain: S7
Length: 179 amino acids
Theoretical weight: 20.1 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Search similar proteins

Chain: V3
Length: 75 amino acids
Theoretical weight: 8.42 KDa
Source organism: Ovis aries
InterPro: NADH-ubiquinone oxidoreductase flavoprotein 3

Search similar proteins

Chain: S6
Length: 96 amino acids
Theoretical weight: 10.65 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Chain: S4
Length: 133 amino acids
Theoretical weight: 15.38 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PE07 (Residues: 38-170; Coverage: 78%)
Gene name: NDUFS4
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
InterPro:

Search similar proteins

Chain: A9
Length: 338 amino acids
Theoretical weight: 38.66 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Chain: A5
Length: 115 amino acids
Theoretical weight: 13.16 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

Search similar proteins

Chain: A6
Length: 127 amino acids
Theoretical weight: 14.92 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5QC06 (Residues: 14-140; Coverage: 91%)
Gene name: NDUFA6
Pfam: Complex 1 protein (LYR family)
InterPro:

Search similar proteins

Chain: A7
Length: 112 amino acids
Theoretical weight: 12.4 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5P0I2 (Residues: 3-114; Coverage: 98%)
Gene name: NDUFA7
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

Search similar proteins

Chain: AL
Length: 145 amino acids
Theoretical weight: 17.12 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Search similar proteins

Chains: AA, AB
Length: 88 amino acids
Theoretical weight: 10.12 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5NQT7 (Residues: 70-157; Coverage: 56%)
Pfam: Phosphopantetheine attachment site
InterPro:

Search similar proteins

Chain: D3
Length: 115 amino acids
Theoretical weight: 13.11 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78753 (Residues: 1-115; Coverage: 100%)
Gene names: MT-ND3, MTND3, NADH3, ND3
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
InterPro:

Search similar proteins

Chain: D1
Length: 318 amino acids
Theoretical weight: 35.88 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78747 (Residues: 1-318; Coverage: 100%)
Gene names: MT-ND1, MTND1, NADH1, ND1
Pfam: NADH dehydrogenase
InterPro:

Search similar proteins

Chain: D6
Length: 175 amino acids
Theoretical weight: 19.13 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78757 (Residues: 1-175; Coverage: 100%)
Gene names: MT-ND6, MTND6, NADH6, ND6
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
InterPro:

Search similar proteins

Chain: 4L
Length: 98 amino acids
Theoretical weight: 10.84 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78754 (Residues: 1-98; Coverage: 100%)
Gene names: MT-ND4L, MTND4L, NADH4L, ND4L
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Chain: D2
Length: 347 amino acids
Theoretical weight: 39.15 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78748 (Residues: 1-347; Coverage: 100%)
Gene names: MT-ND2, MTND2, NADH2, ND2
Pfam:
InterPro:

Search similar proteins

Chain: AK
Length: 140 amino acids
Theoretical weight: 14.61 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

Search similar proteins

Chain: B5
Length: 143 amino acids
Theoretical weight: 16.71 KDa
Source organism: Ovis aries
InterPro: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit

Search similar proteins

Chain: A8
Length: 171 amino acids
Theoretical weight: 20.01 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Chain: BJ
Length: 175 amino acids
Theoretical weight: 20.88 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Search similar proteins

Chain: S5
Length: 105 amino acids
Theoretical weight: 12.47 KDa
Source organism: Ovis aries
InterPro: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5

Search similar proteins

Chain: A3
Length: 83 amino acids
Theoretical weight: 9.19 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

Search similar proteins

Chain: B3
Length: 97 amino acids
Theoretical weight: 11.02 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

Search similar proteins

Chain: C2
Length: 120 amino acids
Theoretical weight: 14.23 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5P9Q8 (Residues: 3-122; Coverage: 98%)
Gene name: NDUFC2
Pfam: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
InterPro: NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2

Search similar proteins

Chain: B4
Length: 128 amino acids
Theoretical weight: 14.98 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5QF73 (Residues: 3-130; Coverage: 99%)
Gene name: NDUFB4
Pfam: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
InterPro: NADH:ubiquinone oxidoreductase, subunit NDUFB4

Search similar proteins

Chain: AM
Length: 143 amino acids
Theoretical weight: 16.64 KDa
Source organism: Ovis aries
InterPro: GRIM-19

Search similar proteins

Chain: B6
Length: 127 amino acids
Theoretical weight: 15.43 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PZE3 (Residues: 2-128; Coverage: 99%)
Gene name: NDUFB6
Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
InterPro: NADH dehydrogenase 1, beta subcomplex, subunit 6

Search similar proteins

Chain: B7
Length: 136 amino acids
Theoretical weight: 16.28 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7

Search similar proteins

Chain: B9
Length: 178 amino acids
Theoretical weight: 21.65 KDa
Source organism: Ovis aries
InterPro:

Search similar proteins

Chain: B8
Length: 158 amino acids
Theoretical weight: 18.82 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5Q1B0 (Residues: 29-186; Coverage: 85%)
Gene name: NDUFB8
Pfam: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
InterPro:

Search similar proteins

Chain: BK
Length: 125 amino acids
Theoretical weight: 14.46 KDa
Source organism: Ovis aries
InterPro: NADH:ubiquinone oxidoreductase, ESSS subunit

Search similar proteins

Chain: C1
Length: 49 amino acids
Theoretical weight: 5.81 KDa
Source organism: Ovis aries
InterPro: NADH-ubiquinone oxidoreductase 1 subunit C1

Search similar proteins

Chain: B1
Length: 57 amino acids
Theoretical weight: 6.93 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, NDUB1

Search similar proteins

Chain: A1
Length: 70 amino acids
Theoretical weight: 8.21 KDa
Source organism: Ovis aries
InterPro: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1

Search similar proteins