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Human endogenous retrovirus (HML2) mature capsid assembly, T=1 icosahedron

Electron Microscopy
2.75Å resolution
PDB entry 6ssj coloured by chain, front view.
PDB entry 6ssj coloured by chain, side view.
PDB entry 6ssj coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo 60-mer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Endogenous retrovirus group K member 24 Gag polyprotein
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Multimeric state: homo 60-mer
Accessible surface area: 656838.03 Å2
Buried surface area: 156069.43 Å2
Dissociation area: 22,604.83 Å2
Dissociation energy (ΔGdiss): -40.27 kcal/mol
Dissociation entropy (TΔSdiss): 184.81 kcal/mol
Symmetry number: 60
PDBe Complex ID: PDB-CPX-158998

Macromolecules

Endogenous retrovirus group K member 24 Gag polyprotein
Chain: A
Length: 248 amino acids
Theoretical weight: 27.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P63145 (Residues: 283-528; Coverage: 37%)
Gene name: ERVK-24
Pfam:
InterPro:
Endogenous retrovirus group K member 24 Gag polyprotein in PDB entry 6ssj, assembly 1, front view.
Endogenous retrovirus group K member 24 Gag polyprotein in PDB entry 6ssj, assembly 1, side view.
Endogenous retrovirus group K member 24 Gag polyprotein in PDB entry 6ssj, assembly 1, top view.
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