GO terms
Biochemical function:
- serotonin binding
- actin filament binding
- nitric-oxide synthase binding
- metal ion binding
- identical protein binding
- sodium ion binding
- cocaine binding
- syntaxin-1 binding
- antiporter activity
- monoamine transmembrane transporter activity
- protein binding
- serotonin:sodium:chloride symporter activity
- neurotransmitter transmembrane transporter activity
- monoatomic cation channel activity
- integrin binding
Biological process:
- conditioned place preference
- neurotransmitter reuptake
- regulation of thalamus size
- cellular response to cGMP
- cellular response to retinoic acid
- platelet aggregation
- membrane depolarization
- serotonin uptake
- brain morphogenesis
- enteric nervous system development
- behavioral response to cocaine
- negative regulation of organ growth
- positive regulation of cell cycle
- negative regulation of neuron differentiation
- sperm ejaculation
- vasoconstriction
- sodium ion transmembrane transport
- response to estradiol
- negative regulation of synaptic transmission, dopaminergic
- negative regulation of cerebellar granule cell precursor proliferation
- monoamine transport
- positive regulation of serotonin secretion
- positive regulation of gene expression
- response to toxic substance
- response to xenobiotic stimulus
- circadian rhythm
- memory
- response to nutrient
- amino acid transport
- serotonin transport
- neurotransmitter transport
- response to hypoxia
Cellular component:
Sequence families
Protein families (Pfam)
![The deposited structure of PDB entry 6vrl contains 1 copy of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth C] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/6vrl_2_C_Pfam_PF07654_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>6vrl</span> contains 1 copy of Pfam domain <span class='highlight'>PF07654 (Immunoglobulin C1-set domain)</span> in <span class='highlight'>Ig-like domain-containing protein</span>. Showing 1 copy in chain <span class='highlight'>B [auth C]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 6vrl contains 1 copy of Pfam domain PF07686 (Immunoglobulin V-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/6vrl_2_C_Pfam_PF07686_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>6vrl</span> contains 1 copy of Pfam domain <span class='highlight'>PF07686 (Immunoglobulin V-set domain)</span> in <span class='highlight'>Ig-like domain-containing protein</span>. Showing 1 copy in chain <span class='highlight'>B [auth C]</span>.")
InterPro annotations
IPR013086
Domain description:
Sodium:neurotransmitter symporter, serotonin, N-terminal
Occurring in:
Occurring in:
IPR003006
Domain description:
Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
Occurring in: