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CryoEM structure of human presequence protease in partial open state 2

Electron Microscopy
3.9Å resolution
PDB entry 6xot coloured by chain, front view.
PDB entry 6xot coloured by chain, side view.
PDB entry 6xot coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Presequence protease, mitochondrial
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Multimeric state: monomeric
Accessible surface area: 40837.05 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-177328

Macromolecules

Presequence protease, mitochondrial
Chain: A
Length: 1014 amino acids
Theoretical weight: 114.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q5JRX3 (Residues: 33-1037; Coverage: 97%)
  • Best match: Q5JRX3-2 (Residues: 33-1038)
Gene names: KIAA1104, MP1, PITRM1, PREP
Pfam:
InterPro:
Presequence protease, mitochondrial in PDB entry 6xot, assembly 1, front view.
Presequence protease, mitochondrial in PDB entry 6xot, assembly 1, side view.
Presequence protease, mitochondrial in PDB entry 6xot, assembly 1, top view.
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