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Head segment of the S.cerevisiae condensin holocomplex in presence of ATP

Electron Microscopy
7.6Å resolution
PDB entry 6yvd coloured by chain, front view.
PDB entry 6yvd coloured by chain, side view.
PDB entry 6yvd coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Assembly composition:
hetero tetramer (preferred)
Entry contents: 4 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
PDBe Complex ID: PDB-CPX-153564

Macromolecules

Condensin complex subunit 2
Chain: B
Length: 811 amino acids
Theoretical weight: 92.73 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38170 (Residues: 1-754; Coverage: 100%)
Gene names: BRN1, YBL0830, YBL097W
Pfam: Condensin complex subunit 2
InterPro: Condensin complex subunit 2/barren
Condensin complex subunit 2 in PDB entry 6yvd, assembly 1, front view.
Condensin complex subunit 2 in PDB entry 6yvd, assembly 1, side view.
Condensin complex subunit 2 in PDB entry 6yvd, assembly 1, top view.
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Condensin complex subunit 3
Chain: A
Length: 1035 amino acids
Theoretical weight: 117.98 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q06680 (Residues: 1-1035; Coverage: 100%)
Gene names: YCG1, YCS5, YDR325W
Pfam: Nuclear condensing complex subunits, C-term domain
InterPro:
Condensin complex subunit 3 in PDB entry 6yvd, assembly 1, front view.
Condensin complex subunit 3 in PDB entry 6yvd, assembly 1, side view.
Condensin complex subunit 3 in PDB entry 6yvd, assembly 1, top view.
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Structural maintenance of chromosomes protein 2
Chain: C
Length: 1170 amino acids
Theoretical weight: 134.13 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38989 (Residues: 1-1170; Coverage: 100%)
Gene names: SMC2, YFR031C
Pfam:
InterPro:
Structural maintenance of chromosomes protein 2 in PDB entry 6yvd, assembly 1, front view.
Structural maintenance of chromosomes protein 2 in PDB entry 6yvd, assembly 1, side view.
Structural maintenance of chromosomes protein 2 in PDB entry 6yvd, assembly 1, top view.
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Structural maintenance of chromosomes protein 4
Chain: D
Length: 1478 amino acids
Theoretical weight: 168.19 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q12267 (Residues: 1-1418; Coverage: 100%)
Gene names: L9449.5, SMC4, YLR086W
Pfam:
InterPro:
Structural maintenance of chromosomes protein 4 in PDB entry 6yvd, assembly 1, front view.
Structural maintenance of chromosomes protein 4 in PDB entry 6yvd, assembly 1, side view.
Structural maintenance of chromosomes protein 4 in PDB entry 6yvd, assembly 1, top view.
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