Structure analysis

S protein of SARS-CoV-2 in complex bound with T-ACE2

Electron Microscopy
4Å resolution
Assembly composition:
hetero hexamer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero hexamer
Accessible surface area: 230087.96 Å2
Buried surface area: 49026.29 Å2
Dissociation area: 2,486.75 Å2
Dissociation energy (ΔGdiss): -17.77 kcal/mol
Dissociation entropy (TΔSdiss): 47.49 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-144664

Macromolecules

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Chains: D, E, F
Length: 655 amino acids
Theoretical weight: 75.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9BYF1 (Residues: 19-615; Coverage: 76%)
Gene names: ACE2, UNQ868/PRO1885
Pfam: Angiotensin-converting enzyme
InterPro:

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