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A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus

X-ray diffraction
2.8Å resolution
PDB entry 7fge coloured by chain, front view.
PDB entry 7fge coloured by chain, side view.
PDB entry 7fge coloured by chain, top view.
Source organism: unidentified influenza virus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Toad na (per)
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Multimeric state: homo tetramer
Accessible surface area: 45290.86 Å2
Buried surface area: 14891.62 Å2
Dissociation area: 5,806.68 Å2
Dissociation energy (ΔGdiss): 26.65 kcal/mol
Dissociation entropy (TΔSdiss): 43.59 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-168284
Assembly 2
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Assembly Name: Toad na (per)
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Multimeric state: homo tetramer
Accessible surface area: 45325.9 Å2
Buried surface area: 14877.12 Å2
Dissociation area: 5,795.53 Å2
Dissociation energy (ΔGdiss): 27.29 kcal/mol
Dissociation entropy (TΔSdiss): 43.59 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-168284

Macromolecules

toad NA (PER)
Chains: A, B, C, D, E, F, G, H
Length: 489 amino acids
Theoretical weight: 53.58 KDa
Source organism: unidentified influenza virus
Expression system: Baculovirus expression vector pFastBac1-HM
InterPro:
toad NA (PER) in PDB entry 7fge, assembly 1, front view.
toad NA (PER) in PDB entry 7fge, assembly 1, side view.
toad NA (PER) in PDB entry 7fge, assembly 1, top view.
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