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Crystal structure of GenB4 in complex with PLP

X-ray diffraction
1.704Å resolution
PDB entry 7lle coloured by chain, front view.
PDB entry 7lle coloured by chain, side view.
PDB entry 7lle coloured by chain, top view.
Source organism: Micromonospora echinospora
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Putative gentamicin aminotransferase IV
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Multimeric state: homo dimer
Accessible surface area: 29862.26 Å2
Buried surface area: 9793.21 Å2
Dissociation area: 4,440.56 Å2
Dissociation energy (ΔGdiss): 69.57 kcal/mol
Dissociation entropy (TΔSdiss): 15.3 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-180282

Macromolecules

Putative gentamicin aminotransferase IV
Chains: A, B
Length: 446 amino acids
Theoretical weight: 49.09 KDa
Source organism: Micromonospora echinospora
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6QVT7 (Residues: 1-445; Coverage: 100%)
Gene names: genB4, gntH
Pfam: Aminotransferase class-III
InterPro:
Putative gentamicin aminotransferase IV in PDB entry 7lle, assembly 1, front view.
Putative gentamicin aminotransferase IV in PDB entry 7lle, assembly 1, side view.
Putative gentamicin aminotransferase IV in PDB entry 7lle, assembly 1, top view.
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