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Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25

Source organisms:
Biochemical function: not assigned
Biological process: entry receptor-mediated virion attachment to host cell
Cellular component: virion membrane

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF11668
Domain description: HCMV glycoprotein pUL130
Occurring in:
  1. Uncharacterized protein UL130
The deposited structure of PDB entry 7m30 contains 1 copy of Pfam domain PF11668 (HCMV glycoprotein pUL130) in Uncharacterized protein UL130. Showing 1 copy in chain C [auth D].

PF01801
Domain description: Cytomegalovirus glycoprotein L
Occurring in:
  1. Envelope glycoprotein L
The deposited structure of PDB entry 7m30 contains 1 copy of Pfam domain PF01801 (Cytomegalovirus glycoprotein L) in Envelope glycoprotein L. Showing 1 copy in chain A [auth B].

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. 2-25 Fab Heavy Chain
  2. 2-25 Fab Light Chain
  3. 1-32 Fab Heavy Chain
  4. 1-32 Fab Light Chain
  5. 1-103 Fab Heavy Chain
  6. 1-103 Fab Light Chain
IPR002689
Domain description: Cytomegalovirus glycoprotein L
Occurring in:
  1. Envelope glycoprotein L
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. 1-103 Fab Light Chain
IPR021038
Domain description: Herpesvirus UL130, cytomegalovirus
Occurring in:
  1. Uncharacterized protein UL130

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