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Cryo-EM structure of a TTYH2 cis-dimer

Electron Microscopy
3.5Å resolution
PDB entry 7rtt coloured by chain, front view.
PDB entry 7rtt coloured by chain, side view.
PDB entry 7rtt coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein tweety homolog 2
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Multimeric state: homo dimer
Accessible surface area: 42602.08 Å2
Buried surface area: 5725.87 Å2
Dissociation area: 1,674.73 Å2
Dissociation energy (ΔGdiss): 18.39 kcal/mol
Dissociation entropy (TΔSdiss): 15.01 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-174816

Macromolecules

Protein tweety homolog 2
Chains: A, B
Length: 540 amino acids
Theoretical weight: 59.94 KDa
Source organism: Mus musculus
Expression system: Mammalia
UniProt:
  • Canonical: Q3TH73 (Residues: 2-532; Coverage: 100%)
Gene name: Ttyh2
Pfam: Tweety
InterPro: Tweety
Protein tweety homolog 2 in PDB entry 7rtt, assembly 1, front view.
Protein tweety homolog 2 in PDB entry 7rtt, assembly 1, side view.
Protein tweety homolog 2 in PDB entry 7rtt, assembly 1, top view.
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