Structure analysis

Crystal Structure of monoclonal S9.6 Fab

X-ray diffraction
2.328Å resolution
Source organism: synthetic construct
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1
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Multimeric state: hetero dimer
Accessible surface area: 18571.8 Å2
Buried surface area: 4170.52 Å2
Dissociation area: 1,809.87 Å2
Dissociation energy (ΔGdiss): 26.6 kcal/mol
Dissociation entropy (TΔSdiss): 13.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214473
Assembly 2 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 19156.33 Å2
Buried surface area: 4461.47 Å2
Dissociation area: 1,921.73 Å2
Dissociation energy (ΔGdiss): 27.99 kcal/mol
Dissociation entropy (TΔSdiss): 13.15 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214473
Assembly 3
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Multimeric state: hetero dimer
Accessible surface area: 19011.16 Å2
Buried surface area: 4568.75 Å2
Dissociation area: 1,869.37 Å2
Dissociation energy (ΔGdiss): 35.5 kcal/mol
Dissociation entropy (TΔSdiss): 13.14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214473

Macromolecules

Chains: A, C, H
Length: 231 amino acids
Theoretical weight: 24.97 KDa
Source organism: synthetic construct
Expression system: Cricetulus griseus
InterPro:

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