Assemblies
Multimeric state:
hetero octamer
Accessible surface area:
728530.62 Å2
Buried surface area:
52225.01 Å2
Dissociation area:
5,867.62
Å2
Dissociation energy (ΔGdiss):
7.67
kcal/mol
Dissociation entropy (TΔSdiss):
49.96
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-159297
Macromolecules
Chains: E, F, G, H
Length: 108 amino acids
Theoretical weight: 11.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase
InterPro:
Length: 108 amino acids
Theoretical weight: 11.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P68106 (Residues: 1-108; Coverage: 100%)
Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase
InterPro:
Chains: A, B, C, D
Length: 4967 amino acids
Theoretical weight: 565.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene name: RYR2
Pfam:
Length: 4967 amino acids
Theoretical weight: 565.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene name: RYR2
Pfam:
- Inositol 1,4,5-trisphosphate/ryanodine receptor
- MIR domain
- RIH domain
- SPRY domain
- RyR domain
- Ryanodine receptor junctional solenoid repeat
- RyR and IP3R Homology associated
- Ryanodine Receptor TM 4-6
- Ion transport protein
- Inositol 1,4,5-trisphosphate/ryanodine receptor
- Ryanodine/Inositol 1,4,5-trisphosphate receptor
- Ryanodine receptor
- MIR motif
- Mir domain superfamily
- RyR/IP3 receptor binding core, RIH domain superfamily
- RIH domain
- B30.2/SPRY domain
- B30.2/SPRY domain superfamily
- Ryanodine receptor, SPRY domain 1
- SPRY domain
- Concanavalin A-like lectin/glucanase domain superfamily
- Ryanodine receptor Ryr
- Ryanodine receptor, SPRY domain 2
- Ryanodine receptor, SPRY domain 3
- RyR/IP3R Homology associated domain
- EF-hand domain pair
- EF-hand domain
- Ryanodine Receptor TM 4-6
- Ion transport domain
