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Structure of HIV-1 capsid declination

Electron Microscopy
3.43Å resolution
PDB entry 7urn coloured by chain, front view.
PDB entry 7urn coloured by chain, side view.
PDB entry 7urn coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Assembly composition:
homo 35-mer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Capsid protein p24
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Multimeric state: homo 35-mer
Accessible surface area: 218885.98 Å2
Buried surface area: 52378.59 Å2
Dissociation area: 1,068.05 Å2
Dissociation energy (ΔGdiss): 27.37 kcal/mol
Dissociation entropy (TΔSdiss): 8.49 kcal/mol
Symmetry number: 5
PDBe Complex ID: PDB-CPX-146188

Macromolecules

Capsid protein p24
Chains: A, L, M, N, O, P, Q
Length: 231 amino acids
Theoretical weight: 25.63 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Pfam:
InterPro:
Capsid protein p24 in PDB entry 7urn, assembly 1, front view.
Capsid protein p24 in PDB entry 7urn, assembly 1, side view.
Capsid protein p24 in PDB entry 7urn, assembly 1, top view.
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