› › Structure analysis

Crystal structure of serotonin 2A receptor in complex with serotonin

X-ray diffraction
3.2Å resolution
PDB entry 7wc4 coloured by chain, front view.
PDB entry 7wc4 coloured by chain, side view.
PDB entry 7wc4 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: 5-hydroxytryptamine receptor 2A
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 18733.89 Å2
Buried surface area: 2269.69 Å2
Dissociation area: 186 Å2
Dissociation energy (ΔGdiss): -3.83 kcal/mol
Dissociation entropy (TΔSdiss): 3.72 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-151176

Macromolecules

5-hydroxytryptamine receptor 2A
Chain: A
Length: 376 amino acids
Theoretical weight: 42.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P28223 (Residues: 67-265, 266-268, 269-288, 289-292, 293-308, 309-403; Coverage: 72%)
Gene names: HTR2, HTR2A
Pfam: 7 transmembrane receptor (rhodopsin family)
InterPro:
5-hydroxytryptamine receptor 2A in PDB entry 7wc4, assembly 1, front view.
5-hydroxytryptamine receptor 2A in PDB entry 7wc4, assembly 1, side view.
5-hydroxytryptamine receptor 2A in PDB entry 7wc4, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links