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An open conformation Form 1 of switch II for RhoA

X-ray diffraction
1.5Å resolution
PDB entry 7wza coloured by chain, front view.
PDB entry 7wza coloured by chain, side view.
PDB entry 7wza coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Transforming protein RhoA
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Multimeric state: monomeric
Accessible surface area: 10044.9 Å2
Buried surface area: 792.64 Å2
Dissociation area: 75.06 Å2
Dissociation energy (ΔGdiss): 12.57 kcal/mol
Dissociation entropy (TΔSdiss): -1.46 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158275

Macromolecules

Transforming protein RhoA
Chain: A
Length: 185 amino acids
Theoretical weight: 20.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61586 (Residues: 1-181; Coverage: 94%)
Gene names: ARH12, ARHA, RHO12, RHOA
Pfam: Ras family
InterPro:
Transforming protein RhoA in PDB entry 7wza, assembly 1, front view.
Transforming protein RhoA in PDB entry 7wza, assembly 1, side view.
Transforming protein RhoA in PDB entry 7wza, assembly 1, top view.
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