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CryoEM structure of chitin synthase 1 from Phytophthora sojae complexed with the nascent chitooligosaccharide

Electron Microscopy
3.9Å resolution
PDB entry 7x05 coloured by chain, front view.
PDB entry 7x05 coloured by chain, side view.
PDB entry 7x05 coloured by chain, top view.
Source organism: Phytophthora sojae strain P6497
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: chitin synthase
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Multimeric state: homo dimer
Accessible surface area: 71782.25 Å2
Buried surface area: 16537.16 Å2
Dissociation area: 5,845.65 Å2
Dissociation energy (ΔGdiss): 88.27 kcal/mol
Dissociation entropy (TΔSdiss): 17.22 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-124468

Macromolecules

Chitin synthase 1
Chains: A, B
Length: 913 amino acids
Theoretical weight: 103.15 KDa
Source organism: Phytophthora sojae strain P6497
Expression system: Homo sapiens
UniProt:
  • Canonical: G4Z2L3 (Residues: 1-913; Coverage: 100%)
Gene names: CHS1, PHYSODRAFT_557500
Pfam: Chitin synthase
InterPro:
chitin synthase in PDB entry 7x05, assembly 1, front view.
chitin synthase in PDB entry 7x05, assembly 1, side view.
chitin synthase in PDB entry 7x05, assembly 1, top view.
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