Assemblies
Multimeric state:
hetero pentamer
Accessible surface area:
47906.57 Å2
Buried surface area:
11620.29 Å2
Dissociation area:
1,103.29
Å2
Dissociation energy (ΔGdiss):
1.09
kcal/mol
Dissociation entropy (TΔSdiss):
12.52
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-225499
Macromolecules
Chain: A
Length: 264 amino acids
Theoretical weight: 30.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene names: GNAS, GNAS1, GSP
Pfam: G-protein alpha subunit
InterPro:
Length: 264 amino acids
Theoretical weight: 30.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene names: GNAS, GNAS1, GSP
Pfam: G-protein alpha subunit
InterPro:
Chain: B
Length: 366 amino acids
Theoretical weight: 39.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: WD domain, G-beta repeat
InterPro:
Length: 366 amino acids
Theoretical weight: 39.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P62873 (Residues: 1-340; Coverage: 100%)
Pfam: WD domain, G-beta repeat
InterPro:
Chain: G
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: GGL domain
InterPro:
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P59768 (Residues: 1-71; Coverage: 100%)
Pfam: GGL domain
InterPro:
Chain: N
Length: 139 amino acids
Theoretical weight: 15.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 139 amino acids
Theoretical weight: 15.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli