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CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)

Source organism: Thermochaetoides thermophila DSM 1495
Biochemical function: NADH dehydrogenase (ubiquinone) activity
Biological process: proton transmembrane transport
Cellular component: mitochondrion

Quick links

EC 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating)

Reaction catalysed:
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Systematic name:
NADH:ubiquinone oxidoreductase
Alternative Name(s):
  • Coenzyme Q reductase
  • Complex 1 dehydrogenase
  • Complex I (NADH:Q1 oxidoreductase)
  • Complex I (electron transport chain)
  • Complex I (mitochondrial electron transport)
  • DPNH-coenzyme Q reductase
  • DPNH-ubiquinone reductase
  • Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase
  • Electron transfer complex I
  • Mitochondrial electron transport complex 1
  • Mitochondrial electron transport complex I
  • NADH coenzyme Q1 reductase
  • NADH dehydrogenase (ubiquinone)
  • NADH-CoQ oxidoreductase
  • NADH-CoQ reductase
  • NADH-Q6 oxidoreductase
  • NADH-coenzyme Q oxidoreductase
  • NADH-coenzyme Q reductase
  • NADH-ubiquinone oxidoreductase
  • NADH-ubiquinone reductase
  • NADH-ubiquinone-1 reductase
  • NADH:ubiquinone oxidoreductase complex
  • Reduced nicotinamide adenine dinucleotide-coenzyme Q reductase
  • Type 1 dehydrogenase
  • Ubiquinone reductase

EC 3.6.4.12: DNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
  • 3' to 5' DNA helicase
  • 3'-5' DNA helicase
  • 3'-5' PfDH
  • 5' to 3' DNA helicase
  • AvDH1
  • BACH1 helicase
  • BLM protein
  • BRCA1-associated C-terminal helicase
  • BcMCM
  • CeWRN-1
  • DNA helicase 120
  • DNA helicase A
  • DNA helicase E
  • DNA helicase II
  • DNA helicase III
  • DNA helicase RECQL5'
  • DNA helicase VI
  • Dbp9p
  • DmRECQ5
  • DnaB
  • DnaB helicase E1
  • HHcsA
  • HPif1
  • Hel E
  • Helicase DnaB
  • Helicase HDH IV
  • Helicase domain of bacteriophage T7 gene 4 protein helicase
  • Hmi1p
  • MCM helicase
  • MCM protein
  • MER3 helicase
  • MER3 protein
  • MPH1
  • PDH120
  • PIF1
  • PcrA
  • PcrA helicase
  • PfDH A
  • Pfh1p
  • UvrD

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00361
Domain description: Proton-conducting membrane transporter
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
  2. NADH-ubiquinone oxidoreductase chain 4
  3. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH:quinone oxidoreductase/Mrp antiporter membrane subunit domain-containing protein. Showing 1 copy in chain B [auth 2].
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 4. Showing 1 copy in chain D [auth 4].
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain E [auth 5].

PF00550
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. Acyl carrier protein
The deposited structure of PDB entry 7zmg contains 2 copies of Pfam domain PF00550 (Phosphopantetheine attachment site) in Acyl carrier protein. Showing 1 copy in chain X [auth Q].

PF09791
Domain description: Oxidoreductase-like protein, N-terminal
Occurring in:
  1. Oxidoreductase-like domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF09791 (Oxidoreductase-like protein, N-terminal) in Oxidoreductase-like domain-containing protein. Showing 1 copy in chain QA [auth o] (this domain is out of the observed residue ranges!).

PF05071
Domain description: NADH ubiquinone oxidoreductase subunit NDUFA12
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF05071 (NADH ubiquinone oxidoreductase subunit NDUFA12) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit. Showing 1 copy in chain MA [auth h].

PF05047
Domain description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Occurring in:
  1. Ribosomal protein/NADH dehydrogenase domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF05047 (Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain) in Ribosomal protein/NADH dehydrogenase domain-containing protein. Showing 1 copy in chain KA [auth f].

PF08122
Domain description: NADH-ubiquinone oxidoreductase B12 subunit family
Occurring in:
  1. Subunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I)
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF08122 (NADH-ubiquinone oxidoreductase B12 subunit family) in Subunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I). Showing 1 copy in chain HA [auth c].

PF05821
Domain description: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
Occurring in:
  1. NADH dehydrogenase (Ubiquinone)-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF05821 (NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)) in NADH dehydrogenase (Ubiquinone)-like protein. Showing 1 copy in chain FA [auth a].

PF04800
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF04800 (NADH dehydrogenase ubiquinone Fe-S protein 4) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. Showing 1 copy in chain DA [auth Y].

PF12853
Domain description: C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF12853 (C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain CA [auth X].

PF10785
Domain description: NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10785 (NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain CA [auth X].

PF06212
Domain description: GRIM-19 protein
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF06212 (GRIM-19 protein) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. Showing 1 copy in chain BA [auth W].

PF06747
Domain description: CHCH domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF06747 (CHCH domain) in NADH-ubiquinone oxidoreductase. Showing 1 copy in chain AA [auth U].

PF10183
Domain description: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Occurring in:
  1. DNA replication ATP-dependent helicase/nuclease DNA2
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10183 (ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. Showing 1 copy in chain Z [auth S].

PF05347
Domain description: Complex 1 protein (LYR family)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF05347 (Complex 1 protein (LYR family)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9. Showing 1 copy in chain Y [auth R].

PF13233
Domain description: Complex1_LYR-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase B14 subunit-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF13233 (Complex1_LYR-like) in Complex 1 LYR protein domain-containing protein. Showing 1 copy in chain W [auth P].

PF10276
Domain description: Zinc-finger domain
Occurring in:
  1. Zinc finger CHCC-type domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10276 (Zinc-finger domain) in Zinc finger CHCC-type domain-containing protein. Showing 1 copy in chain U [auth M].

PF00420
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00420 (NADH-ubiquinone/plastoquinone oxidoreductase chain 4L) in NADH-ubiquinone oxidoreductase chain 4L. Showing 1 copy in chain T [auth L].

PF01058
Domain description: NADH ubiquinone oxidoreductase, 20 Kd subunit
Occurring in:
  1. NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF01058 (NADH ubiquinone oxidoreductase, 20 Kd subunit) in NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein. Showing 1 copy in chain S [auth K].

PF12838
Domain description: 4Fe-4S dicluster domain
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF12838 (4Fe-4S dicluster domain) in 4Fe-4S ferredoxin-type domain-containing protein. Showing 1 copy in chain Q [auth I].

PF01257
Domain description: Thioredoxin-like [2Fe-2S] ferredoxin
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF01257 (Thioredoxin-like [2Fe-2S] ferredoxin) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain P [auth H].

PF00329
Domain description: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
Occurring in:
  1. NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00329 (Respiratory-chain NADH dehydrogenase, 30 Kd subunit) in NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein. Showing 1 copy in chain O [auth G].

PF04716
Domain description: ETC complex I subunit conserved region
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF04716 (ETC complex I subunit conserved region) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain N [auth F].

PF01370
Domain description: NAD dependent epimerase/dehydratase family
Occurring in:
  1. NAD-dependent epimerase/dehydratase domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF01370 (NAD dependent epimerase/dehydratase family) in NAD-dependent epimerase/dehydratase domain-containing protein. Showing 1 copy in chain M [auth E].

PF00346
Domain description: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
Occurring in:
  1. NADH-quinone oxidoreductase subunit D domain-containing protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00346 (Respiratory-chain NADH dehydrogenase, 49 Kd subunit) in NADH-quinone oxidoreductase subunit D domain-containing protein. Showing 1 copy in chain K [auth C].

PF10589
Domain description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10589 (NADH-ubiquinone oxidoreductase-F iron-sulfur binding region) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain J [auth B].

PF10531
Domain description: SLBB domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10531 (SLBB domain) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain J [auth B].

PF22461
Domain description: SLBB domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

PF01512
Domain description: Respiratory-chain NADH dehydrogenase 51 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF01512 (Respiratory-chain NADH dehydrogenase 51 Kd subunit) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain J [auth B].

PF09326
Domain description: NADH-ubiquinone oxidoreductase subunit G, C-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF09326 (NADH-ubiquinone oxidoreductase subunit G, C-terminal) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain I [auth A].

PF00384
Domain description: Molybdopterin oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00384 (Molybdopterin oxidoreductase) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain I [auth A].

PF22151
Domain description: NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein

PF22117
Domain description: NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein

PF10588
Domain description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF10588 (NADH-ubiquinone oxidoreductase-G iron-sulfur binding region) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain I [auth A].

PF13510
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF13510 (2Fe-2S iron-sulfur cluster binding domain) in NADH-ubiquinone oxidoreductase-like protein. Showing 1 copy in chain I [auth A].

PF05676
Domain description: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF05676 (NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. Showing 1 copy in chain G [auth 8].

PF00499
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00499 (NADH-ubiquinone/plastoquinone oxidoreductase chain 6) in NADH-ubiquinone oxidoreductase chain 6. Showing 1 copy in chain F [auth 6].

PF06455
Domain description: NADH dehydrogenase subunit 5 C-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF06455 (NADH dehydrogenase subunit 5 C-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain E [auth 5].

PF00662
Domain description: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00662 (NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain E [auth 5].

PF00507
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00507 (NADH-ubiquinone/plastoquinone oxidoreductase, chain 3) in NADH-ubiquinone oxidoreductase chain 3. Showing 1 copy in chain C [auth 3].

PF00146
Domain description: NADH dehydrogenase
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
The deposited structure of PDB entry 7zmg contains 1 copy of Pfam domain PF00146 (NADH dehydrogenase) in NADH-ubiquinone oxidoreductase chain 1. Showing 1 copy in chain A [auth 1].

InterPro InterPro annotations
IPR003231
Domain description: Acyl carrier protein
Occurring in:
  1. Acyl carrier protein
IPR003918
Domain description: NADH:ubiquinone oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
IPR009081
Domain description: Phosphopantetheine binding ACP domain
Occurring in:
  1. Acyl carrier protein
IPR036736
Domain description: ACP-like superfamily
Occurring in:
  1. Acyl carrier protein
IPR016813
Domain description: NADH-ubiquinone oxidoreductase 21.3 kDa subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR006138
Domain description: NADH-ubiquinone oxidoreductase, 20 Kd subunit
Occurring in:
  1. NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein
IPR017896
Domain description: 4Fe-4S ferredoxin-type, iron-sulphur binding domain
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
IPR010226
Domain description: NADH-quinone oxidoreductase, chain I
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
IPR022885
Domain description: NAD(P)H-quinone oxidoreductase subunit D/H
Occurring in:
  1. NADH-quinone oxidoreductase subunit D domain-containing protein
IPR019574
Domain description: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR000283
Domain description: NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR001750
Domain description: NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
  2. NADH-ubiquinone oxidoreductase chain 4
  3. NADH-ubiquinone oxidoreductase chain 5
IPR001694
Domain description: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
IPR007763
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit
IPR039961
Domain description: NADH-ubiquinone oxidoreductase 9.5kDa subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase 9.5 kDa subunit
IPR007741
Domain description: Ribosomal protein/NADH dehydrogenase domain
Occurring in:
  1. Ribosomal protein/NADH dehydrogenase domain-containing protein
IPR016464
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
Occurring in:
  1. Ribosomal protein/NADH dehydrogenase domain-containing protein
IPR012576
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Occurring in:
  1. Subunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I)
IPR008699
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
Occurring in:
  1. NADH dehydrogenase (Ubiquinone)-like protein
IPR006885
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4 mitochondrial-like
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
IPR009346
Domain description: GRIM-19
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
IPR016680
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8
Occurring in:
  1. NADH-ubiquinone oxidoreductase
IPR008011
Domain description: Complex 1 LYR protein domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase B14 subunit-like protein
  2. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR016488
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase B14 subunit-like protein
IPR006162
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. Acyl carrier protein
IPR017900
Domain description: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
IPR002023
Domain description: NADH-quinone oxidoreductase subunit E-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
  2. Ribosomal protein/NADH dehydrogenase domain-containing protein
IPR010218
Domain description: NADH dehydrogenase, subunit C
Occurring in:
  1. NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
IPR037232
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily
Occurring in:
  1. NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
IPR006806
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR017384
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
Occurring in:
  1. Subunit NDUFA1 of NADH-ubiquinone oxidoreductase (Complex I)
IPR029014
Domain description: [NiFe]-hydrogenase, large subunit
Occurring in:
  1. NADH-quinone oxidoreductase subunit D domain-containing protein
IPR019575
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR037207
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR001949
Domain description: NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR037225
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR001041
Domain description: 2Fe-2S ferredoxin-type iron-sulfur binding domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR008698
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
IPR000440
Domain description: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
IPR018086
Domain description: NADH:ubiquinone oxidoreductase, subunit 1, conserved site
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
IPR019180
Domain description: Oxidoreductase-like, N-terminal
Occurring in:
  1. Oxidoreductase-like domain-containing protein
IPR039251
Domain description: Oxidoreductase-like domain-containing protein 1
Occurring in:
  1. Oxidoreductase-like domain-containing protein
IPR034444
Domain description: NADH-ubiquinone oxidoreductase 17.8kDa subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR044980
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, plant/fungi
Occurring in:
  1. Subunit NDUFB2 of NADH-ubiquinone oxidoreductase (Complex I)
IPR039993
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR038532
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
IPR024549
Domain description: NADH-ubiquinone oxidoreductase, 21kDa subunit, C-terminal, fungi
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR019721
Domain description: NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR010625
Domain description: CHCH
Occurring in:
  1. NADH-ubiquinone oxidoreductase
IPR019329
Domain description: NADH:ubiquinone oxidoreductase, ESSS subunit
Occurring in:
  1. DNA replication ATP-dependent helicase/nuclease DNA2
IPR045292
Domain description: NDUFB9, LYR domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR033034
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR045299
Domain description: NDUFA6, LYR domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase B14 subunit-like protein
IPR019401
Domain description: Zinc finger, CHCC-type
Occurring in:
  1. Zinc finger CHCC-type domain-containing protein
IPR039428
Domain description: NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
IPR001133
Domain description: NADH-ubiquinone oxidoreductase chain 4L/K
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
IPR006137
Domain description: NADH:ubiquinone oxidoreductase-like, 20kDa subunit
Occurring in:
  1. NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein
IPR039205
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR042128
Domain description: NuoE domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR041921
Domain description: NADH-quinone oxidoreductase subunit E, N-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR020396
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
Occurring in:
  1. NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
IPR001268
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit
Occurring in:
  1. NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
IPR008030
Domain description: NmrA-like domain
Occurring in:
  1. NAD-dependent epimerase/dehydratase domain-containing protein
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. NAD-dependent epimerase/dehydratase domain-containing protein
IPR001135
Domain description: NADH-quinone oxidoreductase, subunit D
Occurring in:
  1. NADH-quinone oxidoreductase subunit D domain-containing protein
IPR014029
Domain description: NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
Occurring in:
  1. NADH-quinone oxidoreductase subunit D domain-containing protein
IPR019554
Domain description: Soluble ligand binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR011538
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR011537
Domain description: NADH ubiquinone oxidoreductase, F subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR015405
Domain description: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR006656
Domain description: Molybdopterin oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR006963
Domain description: Molybdopterin oxidoreductase, 4Fe-4S domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR010228
Domain description: NADH:ubiquinone oxidoreductase, subunit G
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR036010
Domain description: 2Fe-2S ferredoxin-like superfamily
Occurring in:
  1. NADH-ubiquinone oxidoreductase-like protein
IPR019342
Domain description: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5
Occurring in:
  1. Subunit NDUFS5 of NADH-ubiquinone oxidoreductase (Complex I)
IPR001457
Domain description: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
IPR042106
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
IPR010934
Domain description: NADH dehydrogenase subunit 5, C-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR001516
Domain description: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR018393
Domain description: NADH-plastoquinone oxidoreductase, chain 5 subgroup
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR003945
Domain description: NADH-quinone oxidoreductase, chain 5-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR010227
Domain description: NADH-quinone oxidoreductase, chain M/4
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
IPR038430
Domain description: NADH:ubiquinone oxidoreductase, subunit 3 superfamily
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
IPR010096
Domain description: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2

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