Assemblies
Assembly Name:
Poly [ADP-ribose] polymerase tankyrase-2
Multimeric state:
homo icosamer
Accessible surface area:
220233.7 Å2
Buried surface area:
68568.15 Å2
Dissociation area:
5,259.2
Å2
Dissociation energy (ΔGdiss):
23.17
kcal/mol
Dissociation entropy (TΔSdiss):
30.19
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-190554
Macromolecules
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 299 amino acids
Theoretical weight: 34.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 299 amino acids
Theoretical weight: 34.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9H2K2 (Residues: 867-1162; Coverage: 25%)
Pfam:
InterPro:
![Poly [ADP-ribose] polymerase tankyrase-2 in PDB entry 8aly, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8aly_entity_1_front_image-200x200.png "Homo 20-meric assembly 1 of PDB entry <span class='highlight'>8aly</span> contains 20 copies of <span class='highlight'>Poly [ADP-ribose] polymerase tankyrase-2</span>. Front view.")
![Poly [ADP-ribose] polymerase tankyrase-2 in PDB entry 8aly, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8aly_entity_1_side_image-200x200.png "Homo 20-meric assembly 1 of PDB entry <span class='highlight'>8aly</span> contains 20 copies of <span class='highlight'>Poly [ADP-ribose] polymerase tankyrase-2</span>. Side view.")
![Poly [ADP-ribose] polymerase tankyrase-2 in PDB entry 8aly, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8aly_entity_1_top_image-200x200.png "Homo 20-meric assembly 1 of PDB entry <span class='highlight'>8aly</span> contains 20 copies of <span class='highlight'>Poly [ADP-ribose] polymerase tankyrase-2</span>. Top view.")