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Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions

Solution NMR
PDB entry 8ar1 coloured by chain, ensemble of 10 models, front view.
PDB entry 8ar1 coloured by chain, ensemble of 10 models, side view.
PDB entry 8ar1 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Toll-like receptor 3
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Multimeric state: monomeric
Accessible surface area: 5587.5 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-518557

Macromolecules

Toll-like receptor 3
Chain: A
Length: 50 amino acids
Theoretical weight: 6.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15455 (Residues: 698-746; Coverage: 6%)
Gene name: TLR3
Pfam: Toll-like receptor 3 trans-membrane domain
InterPro: Toll-like receptor 3 trans-membrane domain
Toll-like receptor 3 in PDB entry 8ar1, assembly 1, front view.
Toll-like receptor 3 in PDB entry 8ar1, assembly 1, side view.
Toll-like receptor 3 in PDB entry 8ar1, assembly 1, top view.
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