Structure analysis

Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1), crystal form 2

X-ray diffraction
3.4Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 17192.39 Å2
Buried surface area: 3779.47 Å2
Dissociation area: 1,889.73 Å2
Dissociation energy (ΔGdiss): 8.79 kcal/mol
Dissociation entropy (TΔSdiss): 13.33 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-246098

Macromolecules

Chain: A
Length: 210 amino acids
Theoretical weight: 23.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9GZX9 (Residues: 26-223; Coverage: 100%)
Gene names: PSEC0250, TSG, TWSG1
Pfam: Twisted gastrulation (Tsg) protein conserved region

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