› 8ddj

Electron Microscopy
3.1Å resolution

Open MscS in PC14.1 Nanodiscs

Released:
DOI: 10.2210/pdb8ddj/pdb
PDB entry 8ddj coloured by chain, front view.
PDB entry 8ddj coloured by chain, side view.
PDB entry 8ddj coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
Park YC, Reddy B, Bavi N, Perozo E, Faraldo-Gómez JD
OpenAccess logo Elife 12 (2023)
PMID: 36715097
Related structures: EMD-27337

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142906 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small-conductance mechanosensitive channel Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 280 amino acids
Theoretical weight: 30.28 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P0C0S1 (Residues: 1-280; Coverage: 98%)
Gene names: JW2891, b2924, mscS, yggB
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-27337
Expression system: Escherichia coli K-12

Quick links

Citations

5 citation in other articles

MOSAICS: A software suite for analysis of membrane structure and dynamics in simulated trajectories.
Bernhardt et al. (2023)
4 more

1 mention without citation

State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
Park et al. (2023)