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Open MscS in PC14.1 Nanodiscs

Electron Microscopy
3.1Å resolution
PDB entry 8ddj coloured by chain, front view.
PDB entry 8ddj coloured by chain, side view.
PDB entry 8ddj coloured by chain, top view.
Source organism: Escherichia coli K-12
Assembly composition:
homo heptamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Small-conductance mechanosensitive channel
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Multimeric state: homo heptamer
Accessible surface area: 95702.71 Å2
Buried surface area: 35024.5 Å2
Dissociation area: 17,512.25 Å2
Dissociation energy (ΔGdiss): 190.06 kcal/mol
Dissociation entropy (TΔSdiss): 92.3 kcal/mol
Symmetry number: 7
PDBe Complex ID: PDB-CPX-142906

Macromolecules

Small-conductance mechanosensitive channel
Chains: A, B, C, D, E, F, G
Length: 280 amino acids
Theoretical weight: 30.28 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P0C0S1 (Residues: 1-280; Coverage: 98%)
Gene names: JW2891, b2924, mscS, yggB
Pfam:
InterPro:
Small-conductance mechanosensitive channel in PDB entry 8ddj, assembly 1, front view.
Small-conductance mechanosensitive channel in PDB entry 8ddj, assembly 1, side view.
Small-conductance mechanosensitive channel in PDB entry 8ddj, assembly 1, top view.
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