Function and Biology

Open MscS in PC14.1 Nanodiscs

Source organism: Escherichia coli K-12
Biochemical function: identical protein binding
Biological process: transmembrane transport
Cellular component: membrane

Sequence families

Pfam Protein families (Pfam)
PF21082
Domain description: Mechanosensitive ion channel MscS, C-terminal
Occurring in:
  1. Small-conductance mechanosensitive channel
The deposited structure of PDB entry 8ddj contains 7 copies of Pfam domain PF21082 (Mechanosensitive ion channel MscS, C-terminal) in Small-conductance mechanosensitive channel. Showing 1 copy in chain A.

PF00924
Domain description: Mechanosensitive ion channel, beta-domain
Occurring in:
  1. Small-conductance mechanosensitive channel
The deposited structure of PDB entry 8ddj contains 7 copies of Pfam domain PF00924 (Mechanosensitive ion channel, beta-domain) in Small-conductance mechanosensitive channel. Showing 1 copy in chain A.

PF21088
Domain description: Mechanosensitive ion channel, transmembrane helices 2/3
Occurring in:
  1. Small-conductance mechanosensitive channel
The deposited structure of PDB entry 8ddj contains 7 copies of Pfam domain PF21088 (Mechanosensitive ion channel, transmembrane helices 2/3) in Small-conductance mechanosensitive channel. Showing 1 copy in chain A.

PF05552
Domain description: Mechanosensitive ion channel, conserved TM helix
Occurring in:
  1. Small-conductance mechanosensitive channel
The deposited structure of PDB entry 8ddj contains 7 copies of Pfam domain PF05552 (Mechanosensitive ion channel, conserved TM helix) in Small-conductance mechanosensitive channel. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR011066
Domain description: Mechanosensitive ion channel MscS, C-terminal domain superfamily
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR006686
Domain description: Mechanosensitive ion channel MscS, conserved site
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR023408
Domain description: Mechanosensitive ion channel MscS, beta-domain superfamily
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR010920
Domain description: LSM domain superfamily
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR006685
Domain description: Mechanosensitive ion channel MscS
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR011014
Domain description: Mechanosensitive ion channel MscS, transmembrane-2
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR008910
Domain description: Mechanosensitive ion channel, conserved TM helix
Occurring in:
  1. Small-conductance mechanosensitive channel
IPR045275
Domain description: Mechanosensitive ion channel MscS, archaea/bacteria type
Occurring in:
  1. Small-conductance mechanosensitive channel