Assemblies
Multimeric state:
hetero tridecamer
Accessible surface area:
159683.64 Å2
Buried surface area:
54871.64 Å2
Dissociation area:
664.98
Å2
Dissociation energy (ΔGdiss):
-25.78
kcal/mol
Dissociation entropy (TΔSdiss):
33.32
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-230600
Macromolecules
Chains: B, H
Length: 739 amino acids
Theoretical weight: 83.18 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam: VEFS-Box of polycomb protein
Length: 739 amino acids
Theoretical weight: 83.18 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q15022 (Residues: 1-739; Coverage: 100%)
Pfam: VEFS-Box of polycomb protein
Chains: C, I
Length: 441 amino acids
Theoretical weight: 50.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam: WD domain, G-beta repeat
Length: 441 amino acids
Theoretical weight: 50.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
O75530 (Residues: 1-441; Coverage: 100%)
Pfam: WD domain, G-beta repeat
Chains: D, J
Length: 425 amino acids
Theoretical weight: 47.71 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam:
Length: 425 amino acids
Theoretical weight: 47.71 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q09028 (Residues: 1-425; Coverage: 100%)
Pfam:
Chains: A, G
Length: 751 amino acids
Theoretical weight: 86.15 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt: Gene names: EZH2, KMT6
Pfam:
Length: 751 amino acids
Theoretical weight: 86.15 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt: Gene names: EZH2, KMT6
Pfam:
Chains: E, K
Length: 1238 amino acids
Theoretical weight: 138.41 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam:
Length: 1238 amino acids
Theoretical weight: 138.41 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
A0A6I9KXB3 (Residues: 1-1238; Coverage: 100%)
Pfam:
Chains: F, L
Length: 517 amino acids
Theoretical weight: 54.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Length: 517 amino acids
Theoretical weight: 54.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q6ZN18 (Residues: 1-517; Coverage: 100%)