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ATP-bound hMRP5 outward-open

Electron Microscopy
3.94Å resolution
PDB entry 8kci coloured by chain, front view.
PDB entry 8kci coloured by chain, side view.
PDB entry 8kci coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: ATP-binding cassette sub-family C member 5
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Multimeric state: monomeric
Accessible surface area: 60184.13 Å2
Buried surface area: 2052.85 Å2
Dissociation area: 140.19 Å2
Dissociation energy (ΔGdiss): 23.93 kcal/mol
Dissociation entropy (TΔSdiss): -2.92 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-246575

Macromolecules

ATP-binding cassette sub-family C member 5
Chain: A
Length: 1437 amino acids
Theoretical weight: 160.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15440 (Residues: 1-1437; Coverage: 100%)
Gene names: ABCC5, MRP5
Pfam:
ATP-binding cassette sub-family C member 5 in PDB entry 8kci, assembly 1, front view.
ATP-binding cassette sub-family C member 5 in PDB entry 8kci, assembly 1, side view.
ATP-binding cassette sub-family C member 5 in PDB entry 8kci, assembly 1, top view.
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