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Nucleotide-bound BSEP in nanodiscs

Electron Microscopy
2.95Å resolution
PDB entry 8pmd coloured by chain, front view.
PDB entry 8pmd coloured by chain, side view.
PDB entry 8pmd coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Bile salt export pump
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Multimeric state: monomeric
Accessible surface area: 46642.75 Å2
Buried surface area: 2146.04 Å2
Dissociation area: 155.9 Å2
Dissociation energy (ΔGdiss): 23.46 kcal/mol
Dissociation entropy (TΔSdiss): -2.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-131895

Macromolecules

Bile salt export pump
Chain: A
Length: 1321 amino acids
Theoretical weight: 146.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O95342 (Residues: 1-1321; Coverage: 100%)
Gene names: ABCB11, BSEP
Pfam:
Bile salt export pump in PDB entry 8pmd, assembly 1, front view.
Bile salt export pump in PDB entry 8pmd, assembly 1, side view.
Bile salt export pump in PDB entry 8pmd, assembly 1, top view.
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