Assemblies
Multimeric state:
hetero hexamer
Accessible surface area:
67162.72 Å2
Buried surface area:
39477.22 Å2
Dissociation area:
1,095.02
Å2
Dissociation energy (ΔGdiss):
10.85
kcal/mol
Dissociation entropy (TΔSdiss):
9.51
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-279872
Macromolecules
Chain: A
Length: 716 amino acids
Theoretical weight: 82.66 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Influenza RNA-dependent RNA polymerase subunit PA
Length: 716 amino acids
Theoretical weight: 82.66 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q3HM39 (Residues: 1-716; Coverage: 100%)
Pfam: Influenza RNA-dependent RNA polymerase subunit PA
Chain: C
Length: 905 amino acids
Theoretical weight: 102.38 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
Pfam:
Length: 905 amino acids
Theoretical weight: 102.38 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q3HM41 (Residues: 1-759; Coverage: 100%)
Pfam:
- Influenza RNA polymerase PB2 N-terminal region
- Influenza RNA polymerase PB2 second domain
- Influenza RNA polymerase PB2 middle domain
- Influenza RNA polymerase PB2 helical domain
- Influenza RNA polymerase PB2 CAP binding domain
- Influenza RNA polymerase PB2 6th domain
- Influenza RNA polymerase PB2 C-terminal domain
Chain: X
Length: 28 amino acids
Theoretical weight: 3.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Pfam: RNA polymerase Rpb1 C-terminal repeat
Length: 28 amino acids
Theoretical weight: 3.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P24928 (Residues: 1713-1740; Coverage: 1%)
Pfam: RNA polymerase Rpb1 C-terminal repeat
Chain: B
Length: 757 amino acids
Theoretical weight: 86.63 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Influenza RNA-dependent RNA polymerase subunit PB1
Length: 757 amino acids
Theoretical weight: 86.63 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q3HM40 (Residues: 1-757; Coverage: 100%)
Pfam: Influenza RNA-dependent RNA polymerase subunit PB1
Name:
RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3')
Representative chains: D
Length: 15 nucleotides
Theoretical weight: 4.86 KDa
Representative chains: D
Length: 15 nucleotides
Theoretical weight: 4.86 KDa
Name:
RNA (5'-R(P*GP*GP*CP*CP*UP*GP*CP*U)-3')
Representative chains: E
Length: 17 nucleotides
Theoretical weight: 5.34 KDa
Representative chains: E
Length: 17 nucleotides
Theoretical weight: 5.34 KDa