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M5PI-bound hMRP5

Electron Microscopy
3.46Å resolution
PDB entry 8wi5 coloured by chain, front view.
PDB entry 8wi5 coloured by chain, side view.
PDB entry 8wi5 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: ATP-binding cassette sub-family C member 5
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Multimeric state: hetero dimer
Accessible surface area: 57104.0 Å2
Buried surface area: 2850.46 Å2
Dissociation area: 1,425.23 Å2
Dissociation energy (ΔGdiss): 8.27 kcal/mol
Dissociation entropy (TΔSdiss): 9.6 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-246576

Macromolecules

ATP-binding cassette sub-family C member 5
Chain: A
Length: 1344 amino acids
Theoretical weight: 150.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15440 (Residues: 94-1437; Coverage: 94%)
Gene names: ABCC5, MRP5
Pfam:
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, front view.
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, side view.
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, top view.
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ATP-binding cassette sub-family C member 5
Chain: B
Length: 24 amino acids
Theoretical weight: 2.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15440 (Residues: 46-69; Coverage: 2%)
Gene names: ABCC5, MRP5
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, front view.
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, side view.
ATP-binding cassette sub-family C member 5 in PDB entry 8wi5, assembly 1, top view.
Molecule details ›

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