› › Structure analysis

Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement)

Electron Microscopy
3.14Å resolution
PDB entry 8woy coloured by chain, front view.
PDB entry 8woy coloured by chain, side view.
PDB entry 8woy coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Spike protein S2' and Angiotensin-converting enzyme
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 37360.7 Å2
Buried surface area: 1842.51 Å2
Dissociation area: 837.76 Å2
Dissociation energy (ΔGdiss): -7.65 kcal/mol
Dissociation entropy (TΔSdiss): 13.11 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-236464

Macromolecules

Angiotensin-converting enzyme
Chain: A
Length: 596 amino acids
Theoretical weight: 69.02 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: G1TEF4 (Residues: 19-614; Coverage: 76%)
Gene name: ACE2
Pfam: Angiotensin-converting enzyme
Angiotensin-converting enzyme in PDB entry 8woy, assembly 1, front view.
Angiotensin-converting enzyme in PDB entry 8woy, assembly 1, side view.
Angiotensin-converting enzyme in PDB entry 8woy, assembly 1, top view.
Molecule details ›

Search similar proteins

Spike protein S1
Chain: B
Length: 229 amino acids
Theoretical weight: 26.08 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 319-539; Coverage: 18%)
Gene names: 2, S
Pfam: Betacoronavirus spike glycoprotein S1, receptor binding
Spike protein S1 in PDB entry 8woy, assembly 1, front view.
Spike protein S1 in PDB entry 8woy, assembly 1, side view.
Spike protein S1 in PDB entry 8woy, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links