Function and Biology

Cryo-EM structure of histamine H1 receptor in complex with histamine and miniGq

Source organisms:
Biochemical function: protein binding
Biological process: G protein-coupled receptor signaling pathway
Cellular component: synapse

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 8yn2 contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 7 copies in chain B.

PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. Histamine H1 receptor
The deposited structure of PDB entry 8yn2 contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in Histamine H1 receptor. Showing 1 copy in chain E [auth R].

PF00631
Domain description: GGL domain
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
The deposited structure of PDB entry 8yn2 contains 1 copy of Pfam domain PF00631 (GGL domain) in Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2. Showing 1 copy in chain C.