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CAPRI: Critical Assessment of PRediction of Interactions

Community wide experiment on the comparative evaluation of protein-protein docking for structure prediction

Hosted By EMBL/EBI-PDBe Group

Results T136

T136 featured 3 interfaces.



Summary for Target 136.1

                         Predictor                                                 Scorer    
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  Nr groups           :        30                                                        16
                           Top-1      Top-3      Top-5      Top-10     Top-100       Top-1            Top-3            Top-5            Top-10          
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  High Accuracy (***) :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Medium         (**) :    24 (24)    68 (25)   111 (25)   210 (25)   210 (25)       12 (12 <-  7)    30 (14 <- 10)    49 (15 <- 13)    95 (16 <- 19)
  Acceptable      (*) :     1 ( 1)     3 ( 2)     4 ( 2)    15 ( 4)    15 ( 4)        3 ( 3 <-  1)    15 ( 9 <-  4)    26 ( 9 <-  4)    59 (13 <-  5)
  Incorrect           :     1 ( 1)     6 ( 4)    13 ( 5)    32 ( 6)    32 ( 6)        0 ( 0 <-  0)     0 ( 0 <-  0)     2 ( 2 <-  1)     3 ( 3 <-  1)
  Clashes             :     4 ( 4)    11 ( 6)    18 ( 7)    31 ( 8)    31 ( 8)        1 ( 1 <-  1)     3 ( 1 <-  3)     3 ( 1 <-  3)     3 ( 1 <-  3)
  Low ID              :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Total               :    30 (30)    88 (30)   146 (30)   288 (30)   288 (30)       16 (16 <-  9)    48 (16 <- 16)    80 (16 <- 18)   160 (16 <- 22)

Link to result details: Result details

Summary for Target 136.2

                         Predictor                                                 Scorer    
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  Nr groups           :        30                                                        16
                           Top-1      Top-3      Top-5      Top-10     Top-100       Top-1            Top-3            Top-5            Top-10          
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  High Accuracy (***) :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Medium         (**) :    15 (15)    38 (20)    62 (21)    96 (21)    96 (21)       11 (11 <-  6)    25 (13 <-  9)    35 (13 <- 10)    56 (15 <- 13)
  Acceptable      (*) :    11 (11)    35 (19)    56 (21)   115 (26)   115 (26)        2 ( 2 <-  2)     8 ( 4 <-  5)    16 ( 9 <-  6)    49 (14 <- 10)
  Incorrect           :     2 ( 2)    12 (10)    21 (13)    57 (18)    57 (18)        3 ( 3 <-  1)    15 ( 9 <-  5)    29 (10 <-  7)    55 (12 <-  8)
  Clashes             :     2 ( 2)     3 ( 2)     7 ( 4)    20 ( 7)    20 ( 7)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Low ID              :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Total               :    30 (30)    88 (30)   146 (30)   288 (30)   288 (30)       16 (16 <-  9)    48 (16 <- 16)    80 (16 <- 18)   160 (16 <- 23)

Link to result details: Result details

Summary for Target 136.3

                         Predictor                                                 Scorer    
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  Nr groups           :        30                                                        16
                           Top-1      Top-3      Top-5      Top-10     Top-100       Top-1            Top-3            Top-5            Top-10          
  --------------------------------------------------------------------------------------------------------------------------------------------------- 
  High Accuracy (***) :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Medium         (**) :     8 ( 8)    17 (11)    24 (13)    32 (14)    32 (14)        6 ( 6 <-  3)     7 ( 7 <-  4)    12 ( 9 <-  6)    21 (11 <-  7)
  Acceptable      (*) :    13 (13)    44 (20)    73 (23)   142 (25)   142 (25)        7 ( 7 <-  6)    31 (15 <- 12)    44 (15 <- 12)    84 (15 <- 15)
  Incorrect           :     8 ( 8)    23 (13)    43 (15)    94 (23)    94 (23)        3 ( 3 <-  1)    10 ( 8 <-  4)    24 (11 <-  7)    55 (15 <- 11)
  Clashes             :     1 ( 1)     4 ( 3)     6 ( 4)    20 ( 6)    20 ( 6)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Low ID              :     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)     0 ( 0)        0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)     0 ( 0 <-  0)
  Total               :    30 (30)    88 (30)   146 (30)   288 (30)   288 (30)       16 (16 <-  9)    48 (16 <- 16)    80 (16 <- 18)   160 (16 <- 22)

Link to result details: Result details

ID mapping

Link ID for all predictors: Predictors
Link ID for all scorers: Scorers

We are announcing the imminent launch of CAPRI Round 45.

We are announcing Round 45 with Target 136.

This target is a novel bacterial lysine decarboxylase LdcA, forming a homo-decamer with D5 symmetry and was determined by cryo-EM. The target is contributed by Irina Gutsche, Institut de Biologies Structurale, Grenoble, France.

This is the first large Cryo-EM complex offered as target to CAPRI. The problem is challenging but should be tractable, given that a good number of related structures are available in the PDB and that information from different templates can be combined. In the detailed target information posted when predictions open some clues will be provided to predictors on the similarities and differences with the structures of homologs.



Documentation and Targets Round 45


Target 136

  • March 13 - registration begins
  • March 20 - prediction Round opens
  • March 23 - deadline for server submissions
  • April 26 - deadline for submitting predictions
  • April 28 - scoring Round set available
  • May 05 - scoring Round submission deadline
In registering, please scrupulously adhere to the registration rules, according to which only team leaders, or teams (with identified members) can submit predictions.

SCORERS

Scorers can download the server set of submissions from
http://cb.iri.univ-lille1.fr/capri/ using the same login user/password as distributed for Capri round45. Full details and deadlines are given on this site.

Email Problems or Queries to Sameer Velankar

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