The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 14 August 2024, EMDB contains 37710 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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(Show all)ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the outward-facing state (OFS)
Capsid of bacteriophage JBD30 decorated with minor capsid protein trimers - asymmetric reconstruction
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP-bound form
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) apo form
Cas1-Cas2 CRISPR integrase bound to prespacer and target DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system
Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5)
Structure of human eIF3 core from closed 48S translation initiation complex
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1
Unsymmetrized map of T5 phage tail tip complex, showing the monomeric Tail Completion Protein p143
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+IMP-bound form, extended
Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State I
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, less-compressed
Structure of human 48S translation initiation complex after eIF5 release (48S-4)
Structure of human 48S translation initiation complex in open codon scanning state (48S-1)
ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.1)
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+IMP-bound form, half-extended
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP-bound form, compressed
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, compressed
Connector complex of empty bacteriophage JBD30 particle computed in C12 symmetry
ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-down)
Myo-inositol-1-phosphate synthase from Thermochaetoides thermophila in complex with NAD
ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS)
ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up)
Cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on one protomer
Capsid of empty bacteriophage JBD30 particle computed in C5 symmetry
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, compressed
Receptor binding protein of bacteriophage JBD30 computed with C3 symmetry
Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph
Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6
Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway)
ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.3)
Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)
ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.2)
The structure of 4 MntR homodimers bound to the promoter sequence of mnep.
Subtomogram averaged decoding-1 state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
CryoEM Structure of Allosterically Switchable De Novo Protein sr312, in Open State with Effector Peptide
Subtomogram averaged unloaded state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Microtubule Protofilament reconstruction in CCP5:microtubule class#3 complex
Structure of eastern equine encephalitis virus VLP in complex with VLDLR LA1
The structure of two MntR dimers bound to the native mnep promoter sequence.
Paired Helical Filament of tau amyloids found in Down Syndrome individuals
Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage
Subtomogram averaged decoding-2 state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Cryo-EM structure of HIV-1 JRFL v6 Env in complex with vaccine-elicited, Membrane Proximal External Region (MPER) directed antibody DH1317.4.
CryoEM Structure of Allosterically Switchable De Novo Protein sr322, In Closed State without Effector Peptide
Subtomogram averaged consensus structure of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Cryo-EM structure of the active Lactococcus lactis Csm bound to target in pre-cleavage stage
Straight Filament of tau amyloids found in Down Syndrome individuals
Subtomogram averaged POST state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Subtomogram averaged classical iPRE state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Straight Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids
Microtubule protofilament reconstruction in CCP5:microtubule class#2 complex
Cryo-EM structure of the rat P2X7 receptor in complex with the high-affinity agonist BzATP
Subtomogram averaged rotated-2 PRE state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab
Microtubule protofilament reconstruction in CCP5:microtubule class#1 complex
CryoEM Structure of Allosterically Switchable De Novo Protein sr322, In Closed State without Effector Peptide, off Target Multimeric State
Cryo-EM structure of the rat P2X7 receptor in the apo closed state purified in the absence of sodium
Subtomogram averaged non-rotated 80S ribosome of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Cryo-EM structure of the rat P2X7 receptor in the apo closed state
Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
Paired Helical Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids
Subtomogram averaged translocation state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Subtomogram averaged rotated-1 PRE state of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes
Structure of 310-18A5 Fab in complex with A/Solomon Islands/3/2006(H1N1) influenza virus hemagglutinin
Structure of eastern equine encephalitis virus VLP unliganded quasi-threefold spike protein
Cryo-EM structure of Dragon Grouper nervous necrosis virion at pH5.0 (4.36A)
Monomer state of SARS-CoV Spike protein complexed with antibody PW5-535
Trimer state of SARS-CoV Spike protein complexed with antibody PW5-535
Structure of SARS-CoV Spike protein complexed with antibody PW5-5
Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs
Monomer state of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Cryo-EM structure of Dragon Grouper nervous necrosis virus-like particle at pH8.0 (3.23A)
The local refined map of SARS-CoV Spike protein complexed with antibody PW5-5
The tetramer complex of DSR2 and tube-forming domain of phage tail tube protein
Cryo-EM structure of Dragon Grouper nervous necrosis virus-like particle at pH5.0 (3.52A)
The local refined map of SARS-CoV-2 Omicron BA.1 Spike complexed with antibody PW5-570
Cryo-EM structure of Dragon Grouper nervous necrosis virion at pH6.5 (3.12A)
Structure of SARS-CoV-2 Omicron BA.1 Spike complexed with antibody PW5-570
The dimer complex of DSR2 and tube-forming domain of phage tail tube protein
Structure of SARS-CoV-2 XBB Variant Spike protein complexed with broadly neutralizing antibody PW5-535
Cryo-EM structure of Dragon Grouper nervous necrosis virus-like particle at pH6.5 (2.82A)
Cryo-EM structure of Hydrogenobacter thermophilus minimal protein-only RNase P (HARP) in complex with pre-tRNAs
State 1 of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
The local refined map of SARS-CoV-2 XBB Variant Spike protein complexed with antibody PW5-535
Composite cryo-EM map of PhiKZ capsid after applying the "block-based" reconstruction method
Icosahedrally averaged cryo-EM reconstruction of PhiKZ capsid before applying the "block-based" reconstruction method
Cryo-EM structure of human gamma-secretase in complex with MK-0752
Cryo-EM structure of human dopamine transporter in complex with dopamine
Cryo-EM structure of human gamma-secretase in complex with BMS906024
Cryo-EM structure of human gamma-secretase in complex with RO4929097
Cryo-EM structure of human dopamine transporter in complex with methylphenidate
Cryo-EM structure of human gamma-secretase in complex with Nirogacestat
structure of a proteinACryo-EM structure of human dopamine transporter in complex with GBR12909
Cryo-EM structure of human dopamine transporter in complex with benztropine
Cryo-EM structure of human gamma-secretase in complex with Crenigacestat
Structure of human TRPV1 in complex with antagonist --protein purified without CHS
cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR
Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)
HK68 cryo-EM structure achieved via rapid-spray and vitrification for grid preparation
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, less-compressed
Cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on one protomer
Capsid of bacteriophage JBD30 decorated with minor capsid protein trimers computed in C5 symmetry
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR
High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
Additional cryo-EM structure of cardiac amyloid AL59 - mixed polymorph
Capsid of bacteriophage JBD30 decorated with minor capsid protein trimers computed in I4 symmetry
ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-up)